KCNH2 Antikörper (AA 751-850)

Produktnummer ABIN6943270

Produktdetails anti-KCNH2 Antikörper

Target: KCNH2 (Potassium Voltage-Gated Channel, Subfamily H (Eag-Related), Member 2 (KCNH2))

Bindungsspezifität: AA 751-850

Reaktivität: Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KCNH2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Kreuzreaktivität: Maus, Ratte

Homologie: Human,Dog,Cow,Sheep,Pig,Horse,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human ERG/KCNH2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu KCNH2

Target: KCNH2 (Potassium Voltage-Gated Channel, Subfamily H (Eag-Related), Member 2 (KCNH2))

Andere Bezeichnung: ERG/KCNH2 (KCNH2 Produkte)

Synonyme: ERG1 antikoerper, HERG antikoerper, HERG1 antikoerper, Kv11.1 antikoerper, LQT2 antikoerper, SQT1 antikoerper, erg antikoerper, KCNH2 antikoerper, ERG antikoerper, gp-erg antikoerper, cerg antikoerper, derg antikoerper, erg1 antikoerper, AI326795 antikoerper, LQT antikoerper, Lqt2 antikoerper, M-erg antikoerper, Merg1 antikoerper, merg1a antikoerper, merg1b antikoerper, potassium voltage-gated channel subfamily H member 2 antikoerper, potassium voltage-gated channel, subfamily H (eag-related), member 6a antikoerper, potassium voltage-gated channel, subfamily H (eag-related), member 2 antikoerper, potassium voltage-gated channel subfamily H member 6 antikoerper, KCNH2 antikoerper, kcnh6a antikoerper, Kcnh2 antikoerper, KCNH6 antikoerper

Hintergrund:

Synonyms: ERG, ERG1, H ERG, HERG 1, HERG, HERG1, LQT 2, LQT2, Potassium channel HERG, SQT1, Voltagegated potassium channel, subfamily H, member 2, KCNH2_HUMAN.

Background: The potassium voltage gated channel, subfamily H (eag related), member 2 (KCNH2) gene encodes a voltage-gated potassium channel which has an important role in cardiac action potential repolarization in the mammalian heart. Mutations in KCNH2 have been shown to cause chromosome 7-linked congenital long QT syndrome, a disorder associated with delayed cardiac repolarization, prolonged electrocardiographic QT intervals, and the development of ventricular arrhythmias. KCNH2 channels are an important target for many drugs, and have emerged as a significant type of cardiac ion channel.Highly expressed in heart and brain.

Gen-ID: 3757

UniProt: Q12809