DYNLL1 Antikörper

Produktnummer ABIN6943170

Produktdetails anti-DYNLL1 Antikörper

Target: DYNLL1 (Dynein, Light Chain, LC8-Type 1 (DYNLL1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser DYNLL1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (Cultured Cells) (IF (cc))

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Purified by Protein A.

Immunogen: N terminus Human DYNLL1

Klon: 9T1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
IF(ICC) 1:50-200
IHC()

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Details zu DYNLL1

Target: DYNLL1 (Dynein, Light Chain, LC8-Type 1 (DYNLL1))

Andere Bezeichnung: DYNLL1 (DYNLL1 Produkte)

Synonyme: DLC1 antikoerper, DLC8 antikoerper, DNCL1 antikoerper, DNCLC1 antikoerper, LC8 antikoerper, LC8a antikoerper, PIN antikoerper, hdlc1 antikoerper, dynll2 antikoerper, wu:fd56c09 antikoerper, zgc:73406 antikoerper, Dlc8 antikoerper, Dnclc1 antikoerper, Pin antikoerper, 8kDLC antikoerper, lc8 antikoerper, dlc1 antikoerper, dlc8 antikoerper, lc8a antikoerper, dncl1 antikoerper, dnclc1 antikoerper, dynll1a antikoerper, MGC68763 antikoerper, CDLC2 antikoerper, dynll1 antikoerper, dynll1b antikoerper, pin antikoerper, MGC89636 antikoerper, dynein light chain LC8-type 1 antikoerper, dynein, light chain, LC8-type 1 antikoerper, dynein light chain LC8-type 1 S homeolog antikoerper, dynein light chain LC8-type 1 L homeolog antikoerper, Dynein light chain 1, cytoplasmic antikoerper, DYNLL1 antikoerper, dynll1 antikoerper, Dynll1 antikoerper, dynll1.S antikoerper, dynll1.L antikoerper, dlc-1 antikoerper

Hintergrund:

Synonyms: Dynein light chain 1, cytoplasmic, 8 kDa dynein light chain, Dynein light chain LC8-type 1, Protein inhibitor of neuronal nitric oxide synthase, DLC8, PIN, DYNLL1

Background: Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in changing or maintaining the spatial distribution of cytoskeletal structures. Binds and inhibits the catalytic activity of neuronal nitric oxide synthase. Promotes transactivation functions of ESR1 and plays a role in the nuclear localization of ESR1. Regulates apoptotic activities of BCL2L11 by sequestering it to microtubules. Upon apoptotic stimuli the BCL2L11-DYNLL1 complex dissociates from cytoplasmic dynein and translocates to mitochondria and sequesters BCL2 thus neutralizing its antiapoptotic activity.

Gen-ID: 8655

UniProt: P63167

Pathways: M Phase, Tube Formation, Positive Regulation of Endopeptidase Activity