DYNLL1 Antikörper (AA 1-89)
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- Target Alle DYNLL1 Antikörper anzeigen
- DYNLL1 (Dynein, Light Chain, LC8-Type 1 (DYNLL1))
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Bindungsspezifität
- AA 1-89
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser DYNLL1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
- Kreuzreaktivität
- Human
- Aufreinigung
- >95%, Protein G purified
- Immunogen
- Recombinant Human Dynein light chain 1, cytoplasmic protein (1-89AA)
- Isotyp
- IgG
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- Applikationshinweise
- Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200, IF:1:50-1:200,
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 - Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- DYNLL1 (Dynein, Light Chain, LC8-Type 1 (DYNLL1))
- Andere Bezeichnung
- DYNLL1 (DYNLL1 Produkte)
- Synonyme
- DLC1 antikoerper, DLC8 antikoerper, DNCL1 antikoerper, DNCLC1 antikoerper, LC8 antikoerper, LC8a antikoerper, PIN antikoerper, hdlc1 antikoerper, dynll2 antikoerper, wu:fd56c09 antikoerper, zgc:73406 antikoerper, Dlc8 antikoerper, Dnclc1 antikoerper, Pin antikoerper, 8kDLC antikoerper, lc8 antikoerper, dlc1 antikoerper, dlc8 antikoerper, lc8a antikoerper, dncl1 antikoerper, dnclc1 antikoerper, dynll1a antikoerper, MGC68763 antikoerper, CDLC2 antikoerper, dynll1 antikoerper, dynll1b antikoerper, pin antikoerper, MGC89636 antikoerper, dynein light chain LC8-type 1 antikoerper, dynein, light chain, LC8-type 1 antikoerper, dynein light chain LC8-type 1 S homeolog antikoerper, dynein light chain LC8-type 1 L homeolog antikoerper, Dynein light chain 1, cytoplasmic antikoerper, DYNLL1 antikoerper, dynll1 antikoerper, Dynll1 antikoerper, dynll1.S antikoerper, dynll1.L antikoerper, dlc-1 antikoerper
- Hintergrund
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Background: Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in changing or maintaining the spatial distribution of cytoskeletal structures. Binds and inhibits the catalytic activity of neuronal nitric oxide synthase. Promotes transactivation functions of ESR1 and plays a role in the nuclear localization of ESR1. Regulates apoptotic activities of BCL2L11 by sequestering it to microtubules. Upon apoptotic stimuli the BCL2L11-DYNLL1 complex dissociates from cytoplasmic dynein and translocates to mitochondria and sequesters BCL2 thus neutralizing its antiapoptotic activity.
Aliases: 8 kDa dynein light chain antibody, 8kDLC antibody, Cytoplasmic dynein light polypeptide antibody, DLC1 antibody, DLC8 antibody, DNCL1 antibody, DNCLC1 antibody, DYL1_HUMAN antibody, Dynein , cytoplasmic, light chain 1 antibody, Dynein light chain 1 cytoplasmic antibody, Dynein light chain 1, cytoplasmic antibody, Dynein light chain LC8 type 1 antibody, Dynein light chain LC8-type 1 antibody, Dynein, cytoplasmic, light polypeptide 1 antibody, Dynein, light chain, LC8-type 1 antibody, DYNLL1 antibody, HDLC1 antibody, LC8 antibody, LC8a antibody, MGC126137 antibody, MGC126138 antibody, MGC72986 antibody, PIN antibody, Protein inhibitor of neuronal nitric oxide synthase antibody, Protein inhibitor of neuronal NOS antibody
- UniProt
- P63167
- Pathways
- M Phase, Tube Formation, Positive Regulation of Endopeptidase Activity
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