AGT Antikörper (AA 51-120) (Cy3)

Produktnummer ABIN6942109

Produktdetails anti-AGT Antikörper (Cy3)

Target: AGT (Angiotensinogen (serpin Peptidase Inhibitor, Clade A, Member 8) (AGT))

Bindungsspezifität: AA 51-120

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser AGT Antikörper ist konjugiert mit Cy3

Applikation: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Flow Cytometry (FACS)

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Angiotensinogen

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: FCM 1:20-100
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu AGT

Target: AGT (Angiotensinogen (serpin Peptidase Inhibitor, Clade A, Member 8) (AGT))

Andere Bezeichnung: Angiotensinogen (AGT Produkte)

Synonyme: ANHU antikoerper, SERPINA8 antikoerper, AI265500 antikoerper, AngI antikoerper, AngII antikoerper, Aogen antikoerper, Serpina8 antikoerper, ANRT antikoerper, Ang antikoerper, PAT antikoerper, wu:fb62f06 antikoerper, wu:fj87b02 antikoerper, zgc:111892 antikoerper, AGT antikoerper, angt antikoerper, ANGT antikoerper, angiotensinogen antikoerper, angiotensinogen (serpin peptidase inhibitor, clade A, member 8) antikoerper, AGT antikoerper, Agt antikoerper, agt antikoerper

Hintergrund:

Synonyms: Angiotenogen, Angiotensinogen, AT, ANGT_HUMNA, Serpin A8

Background: Angiotensinogen protein encoded by this gene, pre-angiotensinogen or angiotensinogen precursor, is expressed in the liver and is cleaved by the enzyme renin in response to lowered blood pressure. The resulting product, angiotensin I is then cleaved by angiotensin converting enzyme (ACE) to generate the physiologically active enzyme angiotensin II. The protein is involved in maintaining blood pressure and in the pathogenesis of essential hypertension and preeclampsia.

Gen-ID: 183

UniProt: P01019

Pathways: JAK-STAT Signalweg, ACE Inhibitor Pathway, EGFR Signaling Pathway, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Regulation of Lipid Metabolism by PPARalpha, Protein targeting to Nucleus, Feeding Behaviour, Monocarboxylic Acid Catabolic Process, Dicarboxylic Acid Transport, Positive Regulation of Response to DNA Damage Stimulus, Regulation of long-term Neuronal Synaptic Plasticity