Rekombinanter MMP3 Antikörper (AA 317-327)

Produktnummer ABIN6936014

Produktdetails anti-MMP3 Antikörper

Target: MMP3 (Matrix Metallopeptidase 3 (Stromelysin 1, Progelatinase) (MMP3))

Antikörpertyp: Recombinant Antibody

Bindungsspezifität: AA 317-327

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser MMP3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Coating (Coat)

Immunogen: Recombinant fragment (around aa 317-327) of human MMP3 protein

Klon: MMP3-1994R

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

Positive Control: Human prostate or lung tissue. A-431 cells.

Known Application: ELISA (For coating, order antibody without BSA), Flow Cytometry (1-2 μg/million cells), Western Blot (0.5-1 μg/mL), Optimal dilution for a specific application should be determined.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 200 μg/mL

Buffer: 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-80 °C

Informationen zur Lagerung: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Haltbarkeit: 24 months

Details zu MMP3

Target: MMP3 (Matrix Metallopeptidase 3 (Stromelysin 1, Progelatinase) (MMP3))

Andere Bezeichnung: MMP3 (MMP3 Produkte)

Synonyme: CHDS6 antikoerper, MMP-3 antikoerper, SL-1 antikoerper, STMY antikoerper, STMY1 antikoerper, STR1 antikoerper, SLN-1 antikoerper, SLN1 antikoerper, STR-1 antikoerper, Stmy1 antikoerper, Str1 antikoerper, MMP10 antikoerper, chds6 antikoerper, mmp-3 antikoerper, mmp13 antikoerper, mmp3 antikoerper, sl-1 antikoerper, stmy antikoerper, stmy1 antikoerper, str1 antikoerper, matrix metallopeptidase 3 antikoerper, matrix metallopeptidase 3 (stromelysin 1, progelatinase) antikoerper, matrix metallopeptidase 3 L homeolog antikoerper, MMP3 antikoerper, Mmp3 antikoerper, mmp3.L antikoerper

Hintergrund: The matrix metalloproteinases (MMP) are a family of peptidase enzymes responsible for the degradation of extracellular matrix components, including collagen, gelatin, fibronectin, laminin and proteoglycan. Transcription of MMP genes is differentially activated by phorbol ester, lipopolysaccharide (LPS) or staphylococcal enterotoxin B (SEB). MMP catalysis requires both calcium and zinc. MMP-3, MMP-10 and MMP-11 (also designated stromelysin-1, 2 and 3, respectively) activate procollagenase. MMP-3 activation of procollagenase can occur via two pathways. Direct activation by MMP-3 is slow and activation by MMP-3 in conjunction with tissue or plasma proteinases is rapid. MMP-10 is expressed in small intestine, and at lower levels in lung and heart. MMP-11 is specifically expressed in stromal cells of breast carcinomas and contributes to epithelial cell malignancies.

Molekulargewicht: 57kDa

Gen-ID: 4314

UniProt: P08254