MMP3 Antikörper (AA 248-477)

Produktnummer ABIN3021709

Zitiert in 1 Publikation. Der Kaninchen Polyklonal anti-MMP3 Antikörper (ABIN3021709) detektiert spezifisch MMP3 in WB, IHC und IF. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für MMP3 Antikörper (AA 248-477) (ABIN3021709)

Target: MMP3 (Matrix Metallopeptidase 3 (Stromelysin 1, Progelatinase) (MMP3))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MMP3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails anti-MMP3 Antikörper

Bindungsspezifität: AA 248-477

Sequenz: RFRLSQDDIN GIQSLYGPPP DSPETPLVPT EPVPPEPGTP ANCDPALSFD AVSTLRGEIL IFKDRHFWRK SLRKLEPELH LISSFWPSLP SGVDAAYEVT SKDLVFIFKG NQFWAIRGNE VRAGYPRGIH TLGFPPTVRK IDAAISDKEK NKTYFFVEDK YWRFDEKRNS MEPGFPKQIA EDFPGIDSKI DAVFEEFGFF YFFTGSSQLE FDPNAKKVTH TLKSNSWLNC

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 248-477 of human MMP3 (NP_002413.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid freeze / thaw cycles

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Referenzen für anti-MMP3 Antikörper (ABIN3021709)

Xia, Zhang, Ge: "C/EBP? Mediates TNF-?-Induced Cancer Cell Migration by Inducing MMP Expression Dependent on p38 MAPK." in: Journal of cellular biochemistry, (2015) (PubMed).

Details zu MMP3

Target: MMP3 (Matrix Metallopeptidase 3 (Stromelysin 1, Progelatinase) (MMP3))

Andere Bezeichnung: MMP3

Hintergrund: Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes an enzyme which degrades fibronectin, laminin, collagens III, IV, IX, and X, and cartilage proteoglycans. The enzyme is thought to be involved in wound repair, progression of atherosclerosis, and tumor initiation. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3.,MMP3,CHDS6,MMP-3,SL-1,STMY,STMY1,STR1,Cancer,Tumor biomarkers,Invasion and Metastasis,Signal Transduction,G protein signaling,G2/M DNA Damage Checkpoint,Cell Biology & Developmental Biology,Cytoskeleton,Extracellular Matrix,MMPs,Ubiquitin,Cardiovascular,Angiogenesis,MMP3

Molekulargewicht: 53 kDa

Gen-ID: 4314

UniProt: P08254