MMP2 Antikörper (AA 444-575)

Produktnummer ABIN6934818

Produktdetails anti-MMP2 Antikörper

Target: MMP2 (Matrix Metalloproteinase 2 (MMP2))

Bindungsspezifität: AA 444-575

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser MMP2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Spezifität: It recognizes a protein of 72 kDa, which is identified as MMP2. The matrix metalloproteinases (MMP) are a family of peptidase enzymes responsible for the degradation of extracellular matrix components, including collagen, gelatin, Fibronectin, Laminin and proteoglycan. Transcription of MMP genes is differentially activated by phorbol ester, lipopolysaccharide (LPS) or staphylococcal enterotoxin B (SEB). MMP catalysis requires both calcium and zinc. MMP-2 (also designated type IV collagenase) cleaves collagen types IV,V, VII and X and gelatin type I. Activation of MMP-2 secretion requires the Ras signaling pathway.

Aufreinigung: Purified by Protein A/G

Immunogen: Recombinant human MMP2 protein fragment (aa 444-575) (exact sequence is proprietary)

Klon: MMP2-1501

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise:

Positive Control: U-138 MG or U-87 MG cells. Placenta or Colon Carcinoma.

Known Application: Western Blot (0.5-1 μg/mL) Optimal dilution for a specific application should be determined.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 200 μg/mL

Buffer: 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-80 °C

Informationen zur Lagerung: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Haltbarkeit: 24 months

Details zu MMP2

Target: MMP2 (Matrix Metalloproteinase 2 (MMP2))

Andere Bezeichnung: MMP2 (MMP2 Produkte)

Synonyme: 2-MMP antikoerper, CG1794 antikoerper, DM2-MMP antikoerper, Dm2-MMP antikoerper, Dmel\\CG1794 antikoerper, MMP2 antikoerper, anon-WO0118547.84 antikoerper, dm-2MMP antikoerper, dmmp2 antikoerper, l(2)02353 antikoerper, mmp2 antikoerper, wu:fa99h12 antikoerper, wu:fk89d01 antikoerper, fgmmp-2 antikoerper, Mmp-2 antikoerper, LOC100135793 antikoerper, Clg4a antikoerper, GelA antikoerper, MMP-2 antikoerper, CLG4 antikoerper, CLG4A antikoerper, MMP-II antikoerper, MONA antikoerper, TBE-1 antikoerper, matrix metallopeptidase 2 antikoerper, Matrix metalloproteinase 2 antikoerper, matrix metalloproteinase 2 antikoerper, matrix metalloproteinase-2 antikoerper, MMP2 antikoerper, Mmp2 antikoerper, mmp2 antikoerper, LOC657982 antikoerper, LOC100135793 antikoerper

Molekulargewicht: 72kDa (Pro), 63kDa (cleaved)

Gen-ID: 4313

UniProt: P08253

Pathways: Activation of Innate immune Response