MMP2 Antikörper

Produktnummer ABIN7249452

Produktdetails anti-MMP2 Antikörper

Target: MMP2 (Matrix Metalloproteinase 2 (MMP2))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MMP2 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC)

Produktmerkmale: Polyclonal Antibody

Aufreinigung: Affinity purification

Immunogen: KLH conjugated Synthetic peptide corresponding to Mouse MMP2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC 1:500-1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.82 mg/mL

Buffer: PBS with 0.02 % sodium azide, 1 % BSA and 50 % glycerol, pH 7.4

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu MMP2

Target: MMP2 (Matrix Metalloproteinase 2 (MMP2))

Andere Bezeichnung: MMP2 (MMP2 Produkte)

Synonyme: 2-MMP antikoerper, CG1794 antikoerper, DM2-MMP antikoerper, Dm2-MMP antikoerper, Dmel\\CG1794 antikoerper, MMP2 antikoerper, anon-WO0118547.84 antikoerper, dm-2MMP antikoerper, dmmp2 antikoerper, l(2)02353 antikoerper, mmp2 antikoerper, wu:fa99h12 antikoerper, wu:fk89d01 antikoerper, fgmmp-2 antikoerper, Mmp-2 antikoerper, LOC100135793 antikoerper, Clg4a antikoerper, GelA antikoerper, MMP-2 antikoerper, CLG4 antikoerper, CLG4A antikoerper, MMP-II antikoerper, MONA antikoerper, TBE-1 antikoerper, matrix metallopeptidase 2 antikoerper, Matrix metalloproteinase 2 antikoerper, matrix metalloproteinase 2 antikoerper, matrix metalloproteinase-2 antikoerper, MMP2 antikoerper, Mmp2 antikoerper, mmp2 antikoerper, LOC657982 antikoerper, LOC100135793 antikoerper

Hintergrund: MMP2,also named as CLG4A,Gelatinase Am,TBE-1 and PEX,belongs to the peptidase M10A family. It is ubiquitinous metalloproteinase that is involved in diverse functions such as remodeling of the vasculature,angiogenesis,tissue repair,tumor invasion,inflammation,and atherosclerotic plaque rupture. MMP2 contributes to myocardial oxidative stress by regulating the activity of GSK3beta. It cleaves GSK3beta in vitro. MMP2 can be cleaved into PEX chain(~60kd).Western blot analysis showed that the 72 kDa and 62 kDa proteinase activities were pro-MMP2 and the active enzyme,respectively.

UniProt: P08253, P33436, P33434

Pathways: Activation of Innate immune Response