TNFRSF18 Antikörper

Produktnummer ABIN6938615

Produktdetails anti-TNFRSF18 Antikörper

Target: TNFRSF18 (Tumor Necrosis Factor Receptor Superfamily, Member 18 (TNFRSF18))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser TNFRSF18 Antikörper ist unkonjugiert

Applikation: ELISA, Coating (Coat)

Spezifität: The tumor necrosis factor receptor (TNFR) superfamily represents a growing family of type I transmembrane glycoproteins that are involved in various cellular functions, including proliferation, differentiation and programmed cell death. These proteins share homology for cysteine-rich repeats in the extracellular ligand binding domain and an intracellular death domain. Members of the TNFR superfamily transmit signals through protein-protein interactions, and these signals can lead to the activation of either the caspase and Jun kinase pathways, which promote cell death, or the NFB signaling pathway.

Kreuzreaktivität (Details): Human.

Aufreinigung: 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

Immunogen: Human full-length TNFRSF18 protein

Klon: GITR-1585

Isotyp: IgG3 kappa

Anwendungsinformationen

Applikationshinweise:

Known_Application: ELISA (For coating, order Ab without BSA & Azide),Optimal dilution for a specific application should be determined.

Positive_Control: Jurkat cells.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Prepared in 10 mM PBS, WITHOUT BSA and Azide.

Konservierungsmittel: Azide free

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

Haltbarkeit: 24 months

Details zu TNFRSF18

Target: TNFRSF18 (Tumor Necrosis Factor Receptor Superfamily, Member 18 (TNFRSF18))

Andere Bezeichnung: TNFRSF18 (TNFRSF18 Produkte)

Synonyme: GITR antikoerper, TNFRSF18 antikoerper, AITR antikoerper, Gitr antikoerper, CD357 antikoerper, GITR-D antikoerper, TNF receptor superfamily member 18 antikoerper, tumor necrosis factor receptor superfamily, member 18 antikoerper, TNFRSF18 antikoerper, Tnfrsf18 antikoerper

Hintergrund: Activation inducible TNFR family receptor, AITR, GITRD, Glucocorticoid induced TNFR related protein, Glucocorticoid-induced TNFR-related protein, TNF receptor superfamily activation inducible protein, TNFRSF18,CD357 / GITR
Cellular localisation: Secreted and Cell Surface

Molekulargewicht: 25kDa

Gen-ID: 8784, 212680

UniProt: Q9Y5U5

Pathways: Cancer Immune Checkpoints