IL3RA Antikörper (AA 26-171)
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- Target Alle IL3RA Antikörper anzeigen
- IL3RA (Interleukin 3 Receptor, alpha (IL3RA))
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Bindungsspezifität
- AA 26-171
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser IL3RA Antikörper ist unkonjugiert
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Applikation
- Immunostaining (ISt), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
- Spezifität
- CD123 is an interleukin 3 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5 (IL5). The binding of this protein to IL3 depends on the beta subunit. The beta subunit is activated by the ligand binding, and is required for the biological activities of IL3. This gene and the gene encoding the colony stimulating factor 2 receptor alpha chain (CSF2RA) form a cytokine receptor gene cluster in a X-Y pseudo-autosomal region on chromosomes X or Y.
- Kreuzreaktivität (Details)
- Human.
- Aufreinigung
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
- Immunogen
- Recombinant fragment of human IL3RA protein (around aa 26-171) (exact sequence is proprietary)
- Klon
- IL3RA-1531
- Isotyp
- IgG2b kappa
- Top Product
- Discover our top product IL3RA Primärantikörper
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- Applikationshinweise
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Known_Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues is enhanced by heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0 for 45 min at 95°C followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.
Positive_Control: THP-1, RPMI-8226 or HDLM-2 cells. Tonsil, Lymph Node or Stomach.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 1.0 mg/mL
- Buffer
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
- Konservierungsmittel
- Azide free
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
- Haltbarkeit
- 24 months
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- Target
- IL3RA (Interleukin 3 Receptor, alpha (IL3RA))
- Andere Bezeichnung
- IL3RA (IL3RA Produkte)
- Synonyme
- CD123 antikoerper, IL3R antikoerper, IL3RAY antikoerper, IL3RX antikoerper, IL3RY antikoerper, hIL-3Ra antikoerper, CDw123 antikoerper, SUT-1 antikoerper, Cyrl antikoerper, interleukin 3 receptor subunit alpha antikoerper, interleukin 3 receptor, alpha chain antikoerper, IL3RA antikoerper, Il3ra antikoerper
- Hintergrund
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CD123, hIL3Ra, IL-3R-alpha, IL-3RA, IL3RAX, IL3RAY, IL3RX, IL3RY, Interleukin-3 Receptor, alpha, Interleukin3 receptor, Interleukin3 receptor, Y-chromosomal,IL3RA / CD123 (Acute Myeloid Leukemia Marker)
Cellular localisation: Cell Surface and Cytoplasmic - Molekulargewicht
- ~70kDa
- Gen-ID
- 3563, 632790
- UniProt
- P26951
- Pathways
- JAK-STAT Signalweg
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