Rekombinanter HLA-DPB1 Antikörper

Produktnummer ABIN6937403

Produktdetails anti-HLA-DPB1 Antikörper

Target: HLA-DPB1 (Major Histocompatibility Complex, Class II, DP beta 1 (HLA-DPB1))

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser HLA-DPB1 Antikörper ist unkonjugiert

Applikation: ELISA, Flow Cytometry (FACS), Immunofluorescence (IF), Coating (Coat)

Spezifität: Recognizes a non-polymorphic determinant of DP-MHC class II. MHC class II antigens are transmembrane glycoproteins of non-covalently linked alpha (33-35 kDa) and beta (27-30 kDa) chains. It reportedly reacts with B- non-T, non-B cell lines but not with T- and myeloid cell lines and leukemias. Differential expression of MHC class II antigens on fetal and adult lymphocytes, malignant B cells appears to reflect the stage of cell differentiation which may be useful in the study of lymphoproliferative disorders.

Kreuzreaktivität (Details): Human.

Aufreinigung: 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

Immunogen: Non-T, non-B human acute lymphoblastic leukemia REH6 cell line

Klon: HLA-DPB1-2862R

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

Known_Application: ELISA (For coating use Ab at 2-4 μg/mL, order Ab without BSA),Flow Cytometry (1-2 μg/million cells),Immunofluorescence (1-2 μg/mL), Optimal dilution for a specific application should be determined.

Positive_Control: Raji cells. Tonsil or lymph node.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Prepared in 10 mM PBS, WITHOUT BSA and Azide.

Konservierungsmittel: Azide free

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

Haltbarkeit: 24 months

Details zu HLA-DPB1

Target: HLA-DPB1 (Major Histocompatibility Complex, Class II, DP beta 1 (HLA-DPB1))

Andere Bezeichnung: HLA-DPB1 (HLA-DPB1 Produkte)

Synonyme: PATR-DPB1 antikoerper, B-LB antikoerper, B-LB2 antikoerper, B-LB21 antikoerper, BLB1 antikoerper, GSP-BLB1 antikoerper, DPB1 antikoerper, HLA-DP antikoerper, HLA-DP1B antikoerper, HLA-DPB antikoerper, major histocompatibility complex, class II, DP beta 1 antikoerper, Major histocompatibility complex class II beta chain BLB1 antikoerper, PATR-DPB1 antikoerper, BLB1 antikoerper, HLA-DPB1 antikoerper

Hintergrund: HLA class II histocompatibility antigen DP alpha 1 chain, HLA DP1A, HLA SB alpha chain, HLADP, HLADPA1, HLASB, HLASB histocompatibility type, Human MHC class II HLA SB alpha, Major histocompatibility complex class II DP alpha 1, MHC class II DP3 alpha, MHC class II DPA1, PLT1, Primed lymphocyte test 1,HLA-DP (MHC II)
Cellular localisation: Cell Surface

Molekulargewicht: 33-35kDa

Gen-ID: 3115, 347270

UniProt: P04440

Pathways: T-Zell Rezeptor Signalweg, Cancer Immune Checkpoints