HLA-DPB1 Antikörper

Produktnummer ABIN7268370

Produktdetails anti-HLA-DPB1 Antikörper

Target: HLA-DPB1 (Major Histocompatibility Complex, Class II, DP beta 1 (HLA-DPB1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HLA-DPB1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Verwendungszweck: HLA-DPB1 Rabbit pAb

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein of Human HLA-DPB1.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IHC,1:50 - 1:100,IF,1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu HLA-DPB1

Target: HLA-DPB1 (Major Histocompatibility Complex, Class II, DP beta 1 (HLA-DPB1))

Andere Bezeichnung: HLA-DPB1 (HLA-DPB1 Produkte)

Synonyme: PATR-DPB1 antikoerper, B-LB antikoerper, B-LB2 antikoerper, B-LB21 antikoerper, BLB1 antikoerper, GSP-BLB1 antikoerper, DPB1 antikoerper, HLA-DP antikoerper, HLA-DP1B antikoerper, HLA-DPB antikoerper, major histocompatibility complex, class II, DP beta 1 antikoerper, Major histocompatibility complex class II beta chain BLB1 antikoerper, PATR-DPB1 antikoerper, BLB1 antikoerper, HLA-DPB1 antikoerper

Hintergrund: HLA-DPB belongs to the HLA class II beta chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DPA) and a beta chain (DPB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26-28 kDa and its gene contains 6 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and exon 5 encodes the cytoplasmic tail. Within the DP molecule both the alpha chain and the beta chain contain the polymorphisms specifying the peptide binding specificities, resulting in up to 4 different molecules. [provided by RefSeq, Jul 2008],DPB1,HLA-DP,HLA-DP1B,HLA-DPB,HLA-DPB1,major histocompatibility complex,class II,DP beta 1,Immunology & Inflammation,HLA-DPB1

Molekulargewicht: 29kDa

Gen-ID: 3115

UniProt: P04440

Pathways: T-Zell Rezeptor Signalweg, Cancer Immune Checkpoints