CSF1R Antikörper (pTyr699) (Cy5.5)

Produktnummer ABIN683763

Produktdetails anti-CSF1R Antikörper (Cy5.5)

Target: CSF1R (Colony Stimulating Factor 1 Receptor (CSF1R))

Bindungsspezifität: pTyr699

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CSF1R Antikörper ist konjugiert mit Cy5.5

Applikation: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic phosphopeptide derived from human CSF1R around the phosphorylation site of tyrosine 699

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P): 1:50-200
Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu CSF1R

Target: CSF1R (Colony Stimulating Factor 1 Receptor (CSF1R))

Andere Bezeichnung: CSF1R (CSF1R Produkte)

Synonyme: AI323359 antikoerper, CD115 antikoerper, CSF-1R antikoerper, Csfmr antikoerper, Fim-2 antikoerper, Fms antikoerper, M-CSF-R antikoerper, M-CSFR antikoerper, C-FMS antikoerper, CSFR antikoerper, FIM2 antikoerper, FMS antikoerper, HDLS antikoerper, PDGFRB antikoerper, MGC89146 antikoerper, CSF-1-R antikoerper, c-fms antikoerper, mrfms antikoerper, CSF1 antikoerper, M-CSF antikoerper, csf1r antikoerper, fms antikoerper, panther antikoerper, colony stimulating factor 1 receptor antikoerper, macrophage colony-stimulating factor receptor antikoerper, colony stimulating factor 1 receptor, a antikoerper, Csf1r antikoerper, CSF1R antikoerper, m-csfr antikoerper, csf1r antikoerper, csf1ra antikoerper

Hintergrund:

Synonyms: C FMS, CD 115, CD115, CD115 antigen, CFMS, Colony stimulating factor 1 receptor, Colony stimulating factor I receptor, CSF 1 R, CSF 1R, CSF1 R , CSF1R , CSFR, FIM 2 , FIM2, CSF1R_HUMAN

Background: This protein tyrosine kinase transmembrane receptor is the receptor for colony stimulating factor 1, a cytokine which controls the production, differentiation, and function of macrophages. This receptor mediates most if not all of the biological effects of this cytokine. Ligand binding activates the receptor kinase through a process of oligomerization and transphosphorylation. The encoded protein is a member of the CSF1/PDGF receptor family of tyrosine protein kinases and contains 5 immunoglobulin like C2 type domains. CD115 is expressed by cells of the monocytic lineage and by progenitor cells. Mutations in this gene have been associated with a predisposition to myeloid malignancy.

Gen-ID: 1436

Pathways: RTK Signalweg, Inositol Metabolic Process, Cell-Cell Junction Organization