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CSF1R Antikörper (AA 344-497)

CSF1R Reaktivität: Human WB, ELISA, IHC, ICC Wirt: Maus Monoclonal 6B9B9 unconjugated
Produktnummer ABIN1724925
  • Target Alle CSF1R Antikörper anzeigen
    CSF1R (Colony Stimulating Factor 1 Receptor (CSF1R))
    Bindungsspezifität
    • 20
    • 20
    • 18
    • 16
    • 16
    • 15
    • 14
    • 11
    • 9
    • 8
    • 7
    • 7
    • 6
    • 6
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 344-497
    Reaktivität
    • 196
    • 140
    • 97
    • 17
    • 8
    • 5
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Wirt
    • 224
    • 30
    • 8
    • 3
    • 2
    Maus
    Klonalität
    • 226
    • 40
    • 1
    Monoklonal
    Konjugat
    • 94
    • 27
    • 15
    • 15
    • 14
    • 11
    • 10
    • 10
    • 9
    • 9
    • 9
    • 9
    • 5
    • 5
    • 5
    • 5
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CSF1R Antikörper ist unkonjugiert
    Applikation
    • 174
    • 106
    • 89
    • 67
    • 50
    • 26
    • 24
    • 21
    • 11
    • 6
    • 5
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC)
    Aufreinigung
    purified
    Immunogen
    Purified recombinant fragment of human CSF1R (AA: 344-497) expressed in E. coli.
    Klon
    6B9B9
    Isotyp
    IgG2b
  • Applikationshinweise
    ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000, ICC: 1:200 - 1:1000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified antibody in PBS with 0.05 % sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    4°C, -20°C for long term storage
  • Morandi, Barbetti, Riverso, Dello Sbarba, Rovida: "The colony-stimulating factor-1 (CSF-1) receptor sustains ERK1/2 activation and proliferation in breast cancer cell lines." in: PLoS ONE, Vol. 6, Issue 11, pp. e27450, (2011) (PubMed).

    Kitagawa, Gouda, Kirii, Sugiyama, Ishihama, Fujii, Narumi, Akita, Yokota: "Characterization of kinase inhibitors using different phosphorylation states of colony stimulating factor-1 receptor tyrosine kinase." in: Journal of biochemistry, Vol. 151, Issue 1, pp. 47-55, (2011) (PubMed).

  • Target
    CSF1R (Colony Stimulating Factor 1 Receptor (CSF1R))
    Andere Bezeichnung
    CSF1R (CSF1R Produkte)
    Synonyme
    AI323359 antikoerper, CD115 antikoerper, CSF-1R antikoerper, Csfmr antikoerper, Fim-2 antikoerper, Fms antikoerper, M-CSF-R antikoerper, M-CSFR antikoerper, C-FMS antikoerper, CSFR antikoerper, FIM2 antikoerper, FMS antikoerper, HDLS antikoerper, PDGFRB antikoerper, MGC89146 antikoerper, CSF-1-R antikoerper, c-fms antikoerper, mrfms antikoerper, CSF1 antikoerper, M-CSF antikoerper, csf1r antikoerper, fms antikoerper, panther antikoerper, colony stimulating factor 1 receptor antikoerper, macrophage colony-stimulating factor receptor antikoerper, colony stimulating factor 1 receptor, a antikoerper, Csf1r antikoerper, CSF1R antikoerper, m-csfr antikoerper, csf1r antikoerper, csf1ra antikoerper
    Hintergrund

    Description: The protein encoded by this gene is the receptor for colony stimulating factor 1, a cytokine which controls the production, differentiation, and function of macrophages. This receptor mediates most if not all of the biological effects of this cytokine. Ligand binding activates the receptor kinase through a process of oligomerization and transphosphorylation. The encoded protein is a tyrosine kinase transmembrane receptor and member of the CSF1/PDGF receptor family of tyrosine-protein kinases. Mutations in this gene have been associated with a predisposition to myeloid malignancy. The first intron of this gene contains a transcriptionally inactive ribosomal protein L7 processed pseudogene oriented in the opposite direction. , , , ,

    Aliases: FMS, CSFR, FIM2, HDLS, C-FMS, CD115, CSF-1R, M-CSF-R

    Molekulargewicht
    108 kDa
    Gen-ID
    1436
    HGNC
    1436
    Pathways
    RTK Signalweg, Inositol Metabolic Process, Cell-Cell Junction Organization
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