CD44 Antikörper (Exon v10) (PE-Cy3)

Produktnummer ABIN680604

Produktdetails anti-CD44 Antikörper (PE-Cy3)

Target: CD44

Bindungsspezifität: Exon v10

Reaktivität: Human, Maus, Ratte, Hund, Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CD44 Antikörper ist konjugiert mit PE-Cy3

Applikation: Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Aufreinigung: Antibodies are purified by protein A and peptide affinity chromatography.

Immunogen: Polyclonal antibodies are produced by immunizing animals with synthetic peptide derived from human CD44v10
Please inquire for sequence information.

Isotyp: IgG

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1mg/1ml

Buffer: 0.01M PBS, pH 7.4 with 10 mg/ml BSA

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Details zu CD44

Target: CD44

Andere Bezeichnung: CD44 (CD44 Produkte)

Synonyme: CDW44 antikoerper, CSPG8 antikoerper, ECMR-III antikoerper, HCELL antikoerper, HUTCH-I antikoerper, IN antikoerper, LHR antikoerper, MC56 antikoerper, MDU2 antikoerper, MDU3 antikoerper, MIC4 antikoerper, Pgp1 antikoerper, AU023126 antikoerper, AW121933 antikoerper, AW146109 antikoerper, HERMES antikoerper, Ly-24 antikoerper, Pgp-1 antikoerper, CD44A antikoerper, METAA antikoerper, RHAMM antikoerper, XCD44 antikoerper, cd44 antikoerper, cdw44 antikoerper, cspg8 antikoerper, ecmr-iii antikoerper, hcell antikoerper, lhr antikoerper, mc56 antikoerper, mdu2 antikoerper, mdu3 antikoerper, mic4 antikoerper, mutch-i antikoerper, pgp1 antikoerper, CD44 molecule (Indian blood group) antikoerper, syndecan 4 antikoerper, CD44 antigen antikoerper, CD44 molecule (Indian blood group) S homeolog antikoerper, CD44 antikoerper, SDC4 antikoerper, Cd44 antikoerper, cd44.S antikoerper

Hintergrund: CD44 is a receptor for hyaluronic acid (HA). It mediates cell-cell and cell-matrix interactions through its affinity for HA and possibly also through its affinity for other ligands such as osteopontin collagens and matrix matalloproteinases (MMPs). Adhesion with HA plays an important role in cell migration tumor growth and progression. Also involved in lymphocyte activation recirculation and homing and in hematopoiesis. Altered expression or dysfunction causes numerous pathogenic phenotypes. Great protein heterogeneity due to numerous alternative splicing and post-translational modification events.
Synonym: ECMR III, Epican, Heparan sulfate proteoglycan, HUTCH I, Hyaluronate receptor, PGP 1, CD44 antigen, CD44 molecule, CDw44, ECMR III, Epican, Extracellular matrix receptor III, GP90 lymphocyte homing/adhesion receptor, Heparan sulfate proteoglycan, Hermes antigen, HUTCH I, Hyaluronate receptor, PGP 1, Phagocytic glycoprotein I.

Molekulargewicht: 82kDa

Gen-ID: 960

Pathways: Glycosaminoglycan Metabolic Process, Autophagie, Negative Regulation of intrinsic apoptotic Signaling