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CD44 Antikörper (AA 21-220)

Name: CD44 Antikörper (AA 21-220)
Brand: antibodies-online
SKU: ABIN7147160
Price: 385 EUR
Availability: InStock

CD44 Reaktivität: Human FACS, WB, IHC, ELISA, IF Wirt: Maus Monoclonal 6G2D2 unconjugated

Western Blot Positive WB detected in: Hela whole cell lysate, HUVEC whole cell lysate, A549 whole cell lysate, MCF-7 whole cell lysate All lanes: CD44 antibody at 1:1500 Secondary Goat polyclonal to Mouse IgG at 1/10000 dilution Predicted band size: 82, 4, 78, 77, 81, 79, 75, 54,47, 40, 44, 33, 74, 76, 38, 16 kDa Observed band size: 95 kDa (CD44 Antikörper (AA 21-220))

Overlay histogram showing Hela cells stained with ABIN7147160 (red line) at 1:200. (CD44 Antikörper (AA 21-220))

FACS

Western Blot Positive WB detected in: A549 whole cell lysate All lanes: CD44 antibody at 1:1000, 1:2000, 1:4000, 1:8000, 1:16000, 1:32000 Secondary Goat polyclonal to Mouse IgG at 1/10000 dilution Predicted band size: 82, 4, 78, 77, 81, 79, 75, 54,47, 40, 44, 33, 74, 76, 38, 16 kDa Observed band size: 95 kDa (CD44 Antikörper (AA 21-220))

IHC image of ABIN7147160 diluted at 1:100 and staining in paraffin-embedded human tonsil tissue performed on a Leica BondTM system. (CD44 Antikörper (AA 21-220))

IHC

IHC image of ABIN7147160 diluted at 1:100 and staining in paraffin-embedded human skin tissue performed on a Leica BondTM system. (CD44 Antikörper (AA 21-220))

IHC

IHC image of ABIN7147160 diluted at 1:100 and staining in paraffin-embedded human breast cancer performed on a Leica BondTM system. (CD44 Antikörper (AA 21-220))

IHC

Immunofluorescence staining of Hela cells with ABIN7147160 at 1:100, counter-stained with DAPI. (CD44 Antikörper (AA 21-220))

Immunofluorescence staining of MCF-7 cells with ABIN7147160 at 1:100, counter-stained with DAPI. (CD44 Antikörper (AA 21-220))

8 Abbildungen

Produktnummer ABIN7147160

Datenblatt (PDF)

Target Alle CD44 Antikörper anzeigen

CD44
Bindungsspezifität
16

16

16

13

10

8

4

4

4

3

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 21-220
Reaktivität
310

170

81

30

25

24

16

11

9

9

8

6

5

4

4

3

2

1

1

1

1

1

1
Human
Wirt
171

124

95

2

1
Maus
Passende Sekundärantikörper
Klonalität
275

116

2
Monoklonal
Konjugat
172

44

31

27

19

9

9

6

6

6

5

5

5

5

5

4

3

3

3

3

3

3

2

2

2

2

1

1

1

1

1

1

1

1

1

1
Dieser CD44 Antikörper ist unkonjugiert
Applikation
274

157

94

76

72

72

61

40

38

31

30

13

9

7

7

6

6

5

4

4

3

3

2

2

2

2

2

1

1

1

1

1

1
Flow Cytometry (FACS), Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Kreuzreaktivität

Human

Aufreinigung

Protein G purified

Immunogen

Recombinant Human CD44 antigen protein (21-220AA)

Klon

6G2D2

Isotyp

IgG1

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anti-CD44 (CD44) (AA 21-259) antibody
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Applikationshinweise

Recommended dilution: WB:1:1000-1:40000, IHC:1:50-1:200, IF:1:50-1:200,

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Buffer

Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel

ProClin

Vorsichtsmaßnahmen

This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung

-20 °C,-80 °C

Informationen zur Lagerung

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target

CD44

Andere Bezeichnung

CD44 (CD44 Produkte)

Synonyme

CDW44 antikoerper, CSPG8 antikoerper, ECMR-III antikoerper, HCELL antikoerper, HUTCH-I antikoerper, IN antikoerper, LHR antikoerper, MC56 antikoerper, MDU2 antikoerper, MDU3 antikoerper, MIC4 antikoerper, Pgp1 antikoerper, AU023126 antikoerper, AW121933 antikoerper, AW146109 antikoerper, HERMES antikoerper, Ly-24 antikoerper, Pgp-1 antikoerper, CD44A antikoerper, METAA antikoerper, RHAMM antikoerper, XCD44 antikoerper, cd44 antikoerper, cdw44 antikoerper, cspg8 antikoerper, ecmr-iii antikoerper, hcell antikoerper, lhr antikoerper, mc56 antikoerper, mdu2 antikoerper, mdu3 antikoerper, mic4 antikoerper, mutch-i antikoerper, pgp1 antikoerper, CD44 molecule (Indian blood group) antikoerper, syndecan 4 antikoerper, CD44 antigen antikoerper, CD44 molecule (Indian blood group) S homeolog antikoerper, CD44 antikoerper, SDC4 antikoerper, Cd44 antikoerper, cd44.S antikoerper

Hintergrund

Background: Receptor for hyaluronic acid (HA). Mediates cell-cell and cell-matrix interactions through its affinity for HA, and possibly also through its affinity for other ligands such as osteopontin, collagens, and matrix metalloproteinases (MMPs). Adhesion with HA plays an important role in cell migration, tumor growth and progression. In cancer cells, may play an important role in invadopodia formation. Also involved in lymphocyte activation, recirculation and homing, and in hematopoiesis. Altered expression or dysfunction causes numerous pathogenic phenotypes. Great protein heterogeneity due to numerous alternative splicing and post-translational modification events. Receptor for LGALS9, the interaction enhances binding of SMAD3 to the FOXP3 promoter, leading to up-regulation of FOXP3 expression and increased induced regulatory T (iTreg) cell stability and suppressive function (By similarity).
Aliases: CD44 antigen, CDw44, Epican, Extracellular matrix receptor III, ECMR-III, GP90 lymphocyte homing/adhesion receptor, HUTCH-I, Heparan sulfate proteoglycan, Hermes antigen, Hyaluronate receptor, Phagocytic glycoprotein 1, PGP-1, Phagocytic glycoprotein I, PGP-I, CD44, CD44, LHR, MDU2, MDU3, MIC4

UniProt

P16070

Pathways

Glycosaminoglycan Metabolic Process, Autophagie, Negative Regulation of intrinsic apoptotic Signaling