PD-1 Antikörper (Alexa Fluor 647)
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- Target Alle PD-1 (PDCD1) Antikörper anzeigen
- PD-1 (PDCD1) (Programmed Cell Death 1 (PDCD1))
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Reaktivität
- Maus
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Wirt
- Ratte
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Klonalität
- Monoklonal
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Konjugat
- Dieser PD-1 Antikörper ist konjugiert mit Alexa Fluor 647
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Applikation
- Flow Cytometry (FACS)
- Klon
- 29F-1A12
- Isotyp
- IgG2a kappa
- Top Product
- Discover our top product PDCD1 Primärantikörper
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 0.5 mg/mL
- Buffer
- PBS with 0.05 % Proclin300, 1 % BSA
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C
- Informationen zur Lagerung
- Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.
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- Target
- PD-1 (PDCD1) (Programmed Cell Death 1 (PDCD1))
- Andere Bezeichnung
- CD279/PD-1 (PDCD1 Produkte)
- Synonyme
- CD279 antikoerper, PD-1 antikoerper, PD1 antikoerper, SLEB2 antikoerper, hPD-1 antikoerper, hPD-l antikoerper, Ly101 antikoerper, Pdc1 antikoerper, programmed cell death 1 antikoerper, PDCD1 antikoerper, Pdcd1 antikoerper
- Hintergrund
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Synonyms: PD-1, Programmed Death-1
Background: CD279, also known as programmed death-1 (PD-1), is a 50-55 kD glycoprotein belonging to the CD28 family of the Ig superfamily. PD-1 is expressed on activated splenic T and B cells and thymocytes. It is induced on activated myeloid cells as well. PD-1 is involved in lymphocyte clonal selection and peripheral tolerance through binding its ligands, B7-H1 (PD-L1) and B7-DC (PD-L2). It has been reported that PD-1 and PD-L1 interactions are critical to positive selection and play a role in shaping the T cell repertoire. PD-L1 negative costimulation is essential for prolonged survival of intratesticular islet allografts.
- Gen-ID
- 18566
- UniProt
- Q02242
- Pathways
- Cancer Immune Checkpoints
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