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PD-1 Antikörper (AA 21-170)

PDCD1 Reaktivität: Human FACS, WB, IHC, ELISA, ICC, Neut Wirt: Maus Monoclonal 3E12A10 unconjugated
Produktnummer ABIN5611149
  • Target Alle PD-1 (PDCD1) Antikörper anzeigen
    PD-1 (PDCD1) (Programmed Cell Death 1 (PDCD1))
    Bindungsspezifität
    • 16
    • 7
    • 5
    • 5
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 21-170
    Reaktivität
    • 143
    • 86
    • 25
    • 5
    • 3
    • 1
    Human
    Wirt
    • 76
    • 71
    • 35
    • 12
    • 9
    • 3
    • 2
    Maus
    Klonalität
    • 149
    • 56
    • 2
    Monoklonal
    Konjugat
    • 98
    • 16
    • 13
    • 11
    • 7
    • 6
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser PD-1 Antikörper ist unkonjugiert
    Applikation
    • 132
    • 58
    • 45
    • 38
    • 38
    • 19
    • 13
    • 13
    • 13
    • 12
    • 10
    • 10
    • 9
    • 8
    • 6
    • 5
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunocytochemistry (ICC), Neutralization (Neut)
    Aufreinigung
    purified
    Immunogen
    Purified recombinant fragment of human PD1 (AA: extra 21-170) expressed in HEK293 cells.
    Klon
    3E12A10
    Isotyp
    IgG2a
    Top Product
    Discover our top product PDCD1 Primärantikörper
  • Applikationshinweise
    ELISA: 1:10000, WB: 1:500 - 1:2000, ICC: 1:200 - 1:1000, FCM: 1:200 - 1:400, IHC: N/A
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified antibody in PBS with 0.05 % sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    4°C, -20°C for long term storage
  • Target
    PD-1 (PDCD1) (Programmed Cell Death 1 (PDCD1))
    Andere Bezeichnung
    PD1 (PDCD1 Produkte)
    Synonyme
    CD279 antikoerper, PD-1 antikoerper, PD1 antikoerper, SLEB2 antikoerper, hPD-1 antikoerper, hPD-l antikoerper, Ly101 antikoerper, Pdc1 antikoerper, programmed cell death 1 antikoerper, PDCD1 antikoerper, Pdcd1 antikoerper
    Hintergrund

    Description: This gene encodes a cell surface membrane protein of the immunoglobulin superfamily. This protein is expressed in pro-B-cells and is thought to play a role in their differentiation. In mice, expression of this gene is induced in the thymus when anti-CD3 antibodies are injected and large numbers of thymocytes undergo apoptosis. Mice deficient for this gene bred on a BALB/c background developed dilated cardiomyopathy and died from congestive heart failure. These studies suggest that this gene product may also be important in T cell function and contribute to the prevention of autoimmune diseases.

    Aliases: PDCD1, PD-1, CD279, SLEB2, hPD-1, hPD-l, hSLE1

    Molekulargewicht
    31.6KD
    Gen-ID
    5133
    HGNC
    5133
    Pathways
    Cancer Immune Checkpoints
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