Bestrophin 1 Antikörper

Produktnummer ABIN7354627

Produktdetails anti-Bestrophin 1 Antikörper

Target: Bestrophin 1 (BEST1)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Bestrophin 1 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS)

Verwendungszweck: Rabbit IgG Polyclonal Anti-Human Bestrophin Antibody DyLight® 550 Conjugated, Flow Validated.

Sequenz: RFIYRLALTE EQQLMFEKLT LYCD

Kreuzreaktivität (Details): No cross reactivity with other proteins.

Produktmerkmale: Rabbit IgG Polyclonal Anti-Human Bestrophin Antibody DyLight® 550 Conjugated, Flow Validated.

Aufreinigung: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence of human Bestrophin (RFIYRLALTEEQQLMFEKLTLYCD).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

Application details: Flow Cytometry|1-3 μg/1x106 cells

Kommentare:

Other applications have not been tested. Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: At 2-8°C for one year. Protect from light. Do not freeze.

Details zu Bestrophin 1

Target: Bestrophin 1 (BEST1)

Andere Bezeichnung: BEST1 (BEST1 Produkte)

Synonyme: CG6264 antikoerper, Dbest antikoerper, Dmel\\CG6264 antikoerper, anon-WO0118547.380 antikoerper, best antikoerper, dBest1 antikoerper, dbest1 antikoerper, dmBest1 antikoerper, BEST1 antikoerper, VMD2 antikoerper, best-1 antikoerper, ARB antikoerper, BEST antikoerper, BMD antikoerper, RP50 antikoerper, TU15B antikoerper, Bmd antikoerper, Vmd2 antikoerper, mBest1 antikoerper, Bestrophin 1 antikoerper, bestrophin 1 antikoerper, Best1 antikoerper, BEST1 antikoerper, best1 antikoerper, Bm1_25500 antikoerper

Hintergrund:

Synonyms: Bestrophin-1, TU15B, Vitelliform macular dystrophy protein 2, BEST1, VMD2

Background: Bestrophin-1 (Best1) is a protein that, in humans, is encoded by the BEST1 gene. This gene encodes a member of the bestrophin gene family. This small gene family is characterized by proteins with a highly conserved N-terminus with four to six transmembrane domains. Bestrophins may form chloride ion channels or may regulate voltage-gated L-type calcium-ion channels. Bestrophins are generally believed to form calcium-activated chloride-ion channels in epithelial cells but they have also been shown to be highly permeable to bicarbonate ion transport in retinal tissue. Mutations in this gene are responsible for juvenile-onset vitelliform macular dystrophy (VMD2), also known as Best macular dystrophy, in addition to adult-onset vitelliform macular dystrophy (AVMD) and other retinopathies. Alternative splicing results in multiple variants encoding distinct isoforms.

Gen-ID: 7439

UniProt: O76090