Bestrophin 1 Antikörper (AA 200-300)

Produktnummer ABIN1678855

Der Kaninchen Polyklonal anti-Bestrophin 1 Antikörper (ABIN1678855) detektiert spezifisch Bestrophin 1 in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für Bestrophin 1 Antikörper (AA 200-300) (ABIN1678855)

Target: Bestrophin 1 (BEST1)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Bestrophin 1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-Bestrophin 1 Antikörper

Bindungsspezifität: AA 200-300

Sequenz: RIRDPILLQS LLNEMNTLRT QCGHLYAYDW ISIPLVYTQV VTVAVYSFFL TCLVGRQFLN PAKAYPGHEL DLVVPVFTFL QFFFYVGWLK VAEQLINPFG E

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: A synthetic peptide corresponding to a sequence within amino acids 200-300 of human BEST1 (NP_004174.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu Bestrophin 1

Target: Bestrophin 1 (BEST1)

Andere Bezeichnung: BEST1

Hintergrund: This gene encodes a member of the bestrophin gene family. This small gene family is characterized by proteins with a highly conserved N-terminus with four to six transmembrane domains. Bestrophins may form chloride ion channels or may regulate voltage-gated L-type calcium-ion channels. Bestrophins are generally believed to form calcium-activated chloride-ion channels in epithelial cells but they have also been shown to be highly permeable to bicarbonate ion transport in retinal tissue. Mutations in this gene are responsible for juvenile-onset vitelliform macular dystrophy (VMD2), also known as Best macular dystrophy, in addition to adult-onset vitelliform macular dystrophy (AVMD) and other retinopathies. Alternative splicing results in multiple variants encoding distinct isoforms.,BEST1,ARB,BEST,BMD,RP50,TU15B,VMD2,Cell Biology & Developmental Biology,Cell Adhesion,Neuroscience,BEST1

Molekulargewicht: 57 kDa/67 kDa/69 kDa

Gen-ID: 7439

UniProt: O76090