beta Amyloid Antikörper (C-Term)

Produktnummer ABIN6658203

Produktdetails anti-beta Amyloid Antikörper

Target: beta Amyloid (Abeta) (Amyloid beta (Abeta))

Bindungsspezifität: C-Term

Reaktivität: Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser beta Amyloid Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Kreuzreaktivität: Maus, Ratte (Rattus)

Kreuzreaktivität (Details): Cross reactivity with beta amyloid from other species has not been determined

Aufreinigung: Anti-Beta Amyloid Antibody is directed against rat Beta Amyloid proteins. The antibody is directed against rat Beta Amyloid. Anti-Beta Amyloid antibody was affinity purified from monospecific antiserum by immunoaffinity purification. . However, reactivity is also expected from the following species based on 100% sequence homology: canine, chicken, human, mouse and non-human primate.

Immunogen:

Immunogen: Anti-Beta Amyloid Antibody was produced by repeated immunizations with synthetic peptide corresponding to amino acid residues from the C-terminal region.

Immunogen Type: Peptide

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

Application Note: Anti-Beta Amyloid antibody is suitable for use in ELISA, Western Blotting. Specific conditions for reactivity should be optimized by the end user. Expect a band of approximately 115 kDa in size corresponding to the APP protein in the appropriate cell lysate or extract.

ELISA Dilution: 1:10,000

Western Blot Dilution: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer:

Buffer: 0.01 M HEPES, 0.15 M Sodium Chloride, pH 7.5

Stabilizer: 0.1 mg/mL Bovine Serum Albumin (BSA) - IgG and Protease free, 50 % (v/v) Glycerol

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store vial at -20° C prior to opening.  This product is stable at 4° C as an undiluted liquid.  For extended storage, aliquot contents and freeze at -20° C or below.  Avoid cycles of freezing and thawing. Dilute only prior to immediate use.

Details zu beta Amyloid

Target: beta Amyloid (Abeta) (Amyloid beta (Abeta))

Andere Bezeichnung: Beta Amyloid (Abeta Produkte)

Synonyme: AAA antikoerper, ABETA antikoerper, ABPP antikoerper, AD1 antikoerper, APPI antikoerper, CTFgamma antikoerper, CVAP antikoerper, PN-II antikoerper, PN2 antikoerper, aaa antikoerper, abeta antikoerper, abpp antikoerper, ad1 antikoerper, appi antikoerper, ctfgamma antikoerper, cvap antikoerper, pn2 antikoerper, Abeta antikoerper, Abpp antikoerper, Adap antikoerper, Ag antikoerper, Cvap antikoerper, E030013M08Rik antikoerper, betaApp antikoerper, amyloid beta precursor protein antikoerper, amyloid beta (A4) precursor protein antikoerper, APP antikoerper, app antikoerper, App antikoerper

Hintergrund:

Synonyms: Amyloid beta A4 protein, ABPP, Alzheimer disease amyloid A4 protein homolog, Amyloidogenic glycoprotein, A-beta, ABeta antibody

Background: Anti-Beta Amyloid antibody recognizes beta amyloid protein also called amyloid precursor protein (APP). A large body of evidence has implicated the APP in the pathogenesis of Alzheimer's disease (AD). The phosphorylation of APP at Thr668 is thought to play a critical role in generation of the soluble APP (beta) and beta-amyloid peptide (abeta) which are the major components of senile plaques in patient brains inflicted with AD. Anti-Beta Amyloid antibody is ideal for investigators involved in Cell Signaling, Neuroscience, Signal Transduction research.

Gene Name: APP

Gen-ID: 54226

UniProt: P08592

Pathways: Inflammasome