SCN8A Antikörper

Produktnummer ABIN6658134

Produktdetails anti-SCN8A Antikörper

Target: SCN8A (Sodium Channel, Voltage-Gated, Type VIII, alpha (SCN8A))

Reaktivität: Ratte

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser SCN8A Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), Immunoprecipitation (IP)

Kreuzreaktivität: Human, Maus, Ratte (Rattus)

Aufreinigung: Anti-Nav1.6 Antibody was purified by Protein G chromatography. A BLAST analysis was used to suggest cross-reactivity with Nav1.6 from Mouse, Human, and Rat based on 100% homology with the immunizing sequence. Cross-reactivity with Nav1.6 from other sources has not been determined. Ion Channels research.

Immunogen:

Immunogen: Nav1.6 Antibody was produced in mice by repeated immunizations raised against a synthetic peptide corresponding to the intracellular interdomain loop I-II of rat Nav1.6.

Immunogen Type: Peptide

Klon: S87A-10

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise:

Immunohistochemistry Dilution: 0.1-1.0 μg/mL

Application Note: Anti-Nav1.6 Antibody is suitable for use in IP and IHC. Specific conditions for reactivity should be optimized by the end user.

Immunoprecipitation Dilution: User Optimized

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer:

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Stabilizer: 50 % (v/v) Glycerol

0.09 % (w/v) Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: RT,4 °C,-20 °C

Informationen zur Lagerung: Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

Details zu SCN8A

Target: SCN8A (Sodium Channel, Voltage-Gated, Type VIII, alpha (SCN8A))

Andere Bezeichnung: Nav1.6 (SCN8A Produkte)

Synonyme: CERIII antikoerper, CIAT antikoerper, EIEE13 antikoerper, MED antikoerper, NaCh6 antikoerper, Nav1.6 antikoerper, PN4 antikoerper, AI853486 antikoerper, C630029C19Rik antikoerper, dmu antikoerper, med antikoerper, mnd-2 antikoerper, mnd2 antikoerper, nmf2 antikoerper, nmf335 antikoerper, nmf58 antikoerper, nur14 antikoerper, seal antikoerper, sodium voltage-gated channel alpha subunit 8 antikoerper, sodium channel, voltage-gated, type VIII, alpha antikoerper, SCN8A antikoerper, Scn8a antikoerper

Hintergrund:

Synonyms: Scn8A, Sodium channel protein type 8 subunit alpha, Peripheral nerve protein type 4, PN4, Sodium channel 6, NaCh6, Sodium channel protein type VIII subunit alpha, Voltage-gated sodium channel subunit alpha Nav1.6

Background: Voltage gated sodium channels initiate action potentials in neurons. Nav1.6 subunits have been assessed to meditate resurgent and persistent sodium currents in cells with a resulting effect on repetitive firing behavior. Nav1.6 subunits have been found to activate at more negative voltages than other Nav subunits.

Gene Name: Scn8a

Gen-ID: 29710

NCBI Accession: NP_062139

UniProt: O88420

Pathways: Sensory Perception of Sound