SCN8A Antikörper (Internal Region)

Produktnummer ABIN6263505

Produktdetails anti-SCN8A Antikörper

Target: SCN8A (Sodium Channel, Voltage-Gated, Type VIII, alpha (SCN8A))

Bindungsspezifität: Internal Region

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SCN8A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Spezifität: Nav1.6/SCN8A Antibody detects endogenous levels of total Nav1.6/SCN8A.

Homologie: Pig,Bovine,Horse,Sheep,Rabbit,Dog

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human Nav1.6/SCN8A, corresponding to a region within the internal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:1000-3000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu SCN8A

Target: SCN8A (Sodium Channel, Voltage-Gated, Type VIII, alpha (SCN8A))

Andere Bezeichnung: SCN8A (SCN8A Produkte)

Synonyme: CERIII antikoerper, CIAT antikoerper, EIEE13 antikoerper, MED antikoerper, NaCh6 antikoerper, Nav1.6 antikoerper, PN4 antikoerper, AI853486 antikoerper, C630029C19Rik antikoerper, dmu antikoerper, med antikoerper, mnd-2 antikoerper, mnd2 antikoerper, nmf2 antikoerper, nmf335 antikoerper, nmf58 antikoerper, nur14 antikoerper, seal antikoerper, sodium voltage-gated channel alpha subunit 8 antikoerper, sodium channel, voltage-gated, type VIII, alpha antikoerper, SCN8A antikoerper, Scn8a antikoerper

Hintergrund:

Description: Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na+ ions may pass in accordance with their electrochemical gradient. In macrophages and melanoma cells, isoform 5 may participate in the control of podosome and invadopodia formation.

Gene: SCN8A

Molekulargewicht: 225 kDa

Gen-ID: 6334

UniProt: Q9UQD0

Pathways: Sensory Perception of Sound