SCN8A Antikörper (C-Term)

Produktnummer ABIN2776200

Produktdetails anti-SCN8A Antikörper

Target: SCN8A (Sodium Channel, Voltage-Gated, Type VIII, alpha (SCN8A))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Kaninchen, Pferd, Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SCN8A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: KSSIFSFRGP GRFRDPGSEN EFADDEHSTV EESEGRRDSL FIPIRARERR

Homologie: Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against SCN8A. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of human SCN8A

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeat freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu SCN8A

Target: SCN8A (Sodium Channel, Voltage-Gated, Type VIII, alpha (SCN8A))

Andere Bezeichnung: SCN8A (SCN8A Produkte)

Synonyme: CERIII antikoerper, CIAT antikoerper, EIEE13 antikoerper, MED antikoerper, NaCh6 antikoerper, Nav1.6 antikoerper, PN4 antikoerper, AI853486 antikoerper, C630029C19Rik antikoerper, dmu antikoerper, med antikoerper, mnd-2 antikoerper, mnd2 antikoerper, nmf2 antikoerper, nmf335 antikoerper, nmf58 antikoerper, nur14 antikoerper, seal antikoerper, sodium voltage-gated channel alpha subunit 8 antikoerper, sodium channel, voltage-gated, type VIII, alpha antikoerper, SCN8A antikoerper, Scn8a antikoerper

Hintergrund: This gene encodes a member of the sodium channel alpha subunit gene family. The encoded protein forms the ion pore region of the voltage-gated sodium channel. This protein is essential for the rapid membrane depolarization that occurs during the formation of the action potential in excitable neurons. Mutations in this gene are associated with mental retardation, pancerebellar atrophy and ataxia. Alternate splicing results in multiple transcript variants.
Alias Symbols: MED, PN4, CIAT, NaCh6, CERIII, EIEE13, Nav1.6
Protein Size: 475

Molekulargewicht: 52 kDa

Gen-ID: 6334

NCBI Accession: NM_001177984, NP_001171455

UniProt: Q9UQD0

Pathways: Sensory Perception of Sound