PIAS4 Antikörper (N-Term)
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- Target Alle PIAS4 Antikörper anzeigen
- PIAS4 (Protein Inhibitor of Activated STAT, 4 (PIAS4))
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Bindungsspezifität
- AA 44-73, N-Term
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Reaktivität
- Maus
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser PIAS4 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Aufreinigung
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- Immunogen
- This PIAS4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 44-73 amino acids from the N-terminal region of human PIAS4.
- Klon
- RB33956
- Isotyp
- Ig Fraction
- Top Product
- Discover our top product PIAS4 Primärantikörper
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- Applikationshinweise
- WB: 1:1000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- PIAS4 Antibody (N-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
- Haltbarkeit
- 6 months
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- Target
- PIAS4 (Protein Inhibitor of Activated STAT, 4 (PIAS4))
- Andere Bezeichnung
- PIAS4 (PIAS4 Produkte)
- Synonyme
- PIASY antikoerper, Piasg antikoerper, ZMIZ6 antikoerper, pias4 antikoerper, piasy antikoerper, wu:fc54c11 antikoerper, wu:fi18c10 antikoerper, wu:fi20e09 antikoerper, wu:fk93f11 antikoerper, zgc:66410 antikoerper, piasg antikoerper, zmiz6 antikoerper, LOC100219439 antikoerper, Pias-gamma antikoerper, pias4l antikoerper, wu:fi26h11 antikoerper, zgc:63923 antikoerper, protein inhibitor of activated STAT 4 antikoerper, protein inhibitor of activated STAT, 4 antikoerper, protein inhibitor of activated STAT, 4a antikoerper, protein inhibitor of activated STAT 4 L homeolog antikoerper, protein inhibitor of activated STAT, 4b antikoerper, PIAS4 antikoerper, Pias4 antikoerper, pias4a antikoerper, pias4.L antikoerper, pias4 antikoerper, pias4b antikoerper
- Hintergrund
- PIAS4 functions as an E3-type small ubiquitin-like modifier (SUMO) ligase, stabilizing the interaction between UBE2I and the substrate, and as a SUMO-tethering factor. Plays a crucial role as a transcriptional coregulation in various cellular pathways, including the STAT pathway, the p53 pathway, the Wnt pathway and the steroid hormone signaling pathway. Involved in gene silencing. Promotes PARK7 sumoylation. In Wnt signaling, represses LEF1 and enhances TCF4 transcriptional activities through promoting their sumoylations.
- Molekulargewicht
- 56504
- Gen-ID
- 51588
- NCBI Accession
- NP_056981
- UniProt
- Q8N2W9
- Pathways
- JAK-STAT Signalweg, Interferon-gamma Pathway, Positive Regulation of Response to DNA Damage Stimulus
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