PIAS4 Produkte
(Protein Inhibitor of Activated STAT, 4 (PIAS4))
Kategorien
Functions as an E3-type small ubiquitin-like modifier (SUMO) ligase, stabilizing the interaction between UBE2I and the substrate, and as a SUMO-tethering factor. Plays a crucial role as a transcriptional coregulation in various cellular pathways, including the STAT pathway, the p53 pathway, the Wnt pathway and the steroid hormone signaling pathway. Involved in gene silencing. Promotes PARK7 sumoylation. In Wnt signaling, represses LEF1 and enhances TCF4 transcriptional activities through promoting their sumoylations.
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Ausgewählte PIAS4 Kategorien
PIAS4 Antikörper
High quality antibodies with extensive validation data.
PIAS4 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene PIAS4 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, IHC (p)
Validierungen
- (2)
- (2)
Kat. Nr.
ABIN388061
Menge
400 μL
Datenblatt
Datenblatt
Reaktivität
Human, Mouse, Rat
Applikation
WB, ELISA, IHC, IF, ICC
Validierungen
- (3)
Kat. Nr.
ABIN6264199
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IHC (p)
Validierungen
- (2)
Kat. Nr.
ABIN388062
Menge
400 μL
Datenblatt
Datenblatt
Empfohlene PIAS4 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human, Mouse
Analytical Method
Qualitative Cell ELISA
Validierungen
Kat. Nr.
ABIN1381423
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene PIAS4 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
- (1)
Kat. Nr.
ABIN7124650
Menge
50 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1314996
Menge
25 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Insect Cells
Validierungen
- (1)
Kat. Nr.
ABIN3094653
Menge
1 mg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren PIAS4 Produkten
: "SUMOylation proteins in breast cancer." in: Breast cancer research and treatment, Vol. 144, Issue 3, pp. 519-30, (2014) (PubMed).: "Activation of the SUMO modification system is required for the accumulation of RAD51 at sites of DNA damage." in: Journal of cell science, Vol. 126, Issue Pt 22, pp. 5284-92, (2013) (PubMed).
: "Caveolin-3 undergoes SUMOylation by the SUMO E3 ligase PIASy: sumoylation affects G-protein-coupled receptor desensitization." in: The Journal of biological chemistry, Vol. 286, Issue 17, pp. 14830-41, (2011) (PubMed).
: "DNA ploidy cytometry testing for cervical cancer screening in China (DNACIC Trial): a prospective randomized, controlled trial." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 15, Issue 20, pp. 6438-45, (2009) (PubMed).
: "Developmental control of sumoylation pathway proteins in mouse male germ cells." in: Developmental biology, Vol. 321, Issue 1, pp. 227-37, (2008) (PubMed).
: "MUC1 expression is repressed by protein inhibitor of activated signal transducer and activator of transcription-y." in: Molecular endocrinology (Baltimore, Md.), Vol. 21, Issue 11, pp. 2725-37, (2007) (PubMed).
: "The interaction of Piasy with Trim32, an E3-ubiquitin ligase mutated in limb-girdle muscular dystrophy type 2H, promotes Piasy degradation and regulates UVB-induced keratinocyte apoptosis through ..." in: The Journal of biological chemistry, Vol. 281, Issue 35, pp. 25850-66, (2006) (PubMed).
: "The E3 SUMO ligase PIASy is a regulator of cellular senescence and apoptosis." in: Molecular cell, Vol. 22, Issue 6, pp. 783-94, (2006) (PubMed).
: "SUMO-1 modification of PIASy, an E3 ligase, is necessary for PIASy-dependent activation of Tcf-4." in: Molecular and cellular biology, Vol. 25, Issue 9, pp. 3506-18, (2005) (PubMed).
: "PIASy represses TRIF-induced ISRE and NF-kappaB activation but not apoptosis." in: FEBS letters, Vol. 570, Issue 1-3, pp. 97-101, (2004) (PubMed).
Synonyme und alternative Namen zu PIAS4
protein inhibitor of activated STAT 4 (PIAS4), protein inhibitor of activated STAT, 4 (Pias4), protein inhibitor of activated STAT, 4a (pias4a), protein inhibitor of activated STAT 4 L homeolog (pias4.L), protein inhibitor of activated STAT 4 (pias4), protein inhibitor of activated STAT 4 (Pias4), protein inhibitor of activated STAT, 4b (pias4b), LOC100219439, Pias-gamma, pias4, pias4l, Piasg, piasg, PIASY, piasy, wu:fc54c11, wu:fi18c10, wu:fi20e09, wu:fi26h11, wu:fk93f11, zgc:63923, zgc:66410, ZMIZ6, zmiz6Bezeichner auf Proteinebene für PIAS4
- E3 SUMO-protein ligase PIAS4
- PIAS-gamma
- protein inhibitor of activated STAT protein 4
- protein inhibitor of activated STAT protein PIASy
- protein inhibitor of activated STAT protein gamma
- zinc finger, MIZ-type containing 6
- protein inhibitor of activated STAT 4
- protein inhibitor of activated STAT, 4
- E3 SUMO-protein ligase PIAS4-like
- e3 SUMO-protein ligase PIAS4-like
- protein inhibitor of activated STAT PIASy
- protein inhibitor of activated STAT, 4b
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