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PI3 Produkte

(Peptidase Inhibitor 3, Skin-Derived, PI3)

Kategorien

This gene encodes an elastase-specific inhibitor that functions as an antimicrobial peptide against Gram-positive and Gram-negative bacteria. The protein contains a WAP-type four-disulfide core (WFDC) domain, and is thus a member of the WFDC domain family. Most WFDC gene members are localized to chromosome 20q12-q13 in two clusters: centromeric and telomeric. This gene belongs to the centromeric cluster. Expression of this gene is upgulated by bacterial lipopolysaccharides and cytokines. [provided by RefSeq, Oct 2008].

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Ausgewählte PI3 Kategorien

PI3 Antikörper

High quality antibodies with extensive validation data.

PI3 ELISA Kits

Reliable ELISA kits for a wide range of species.

PI3 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene PI3 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
ReaktivitätHuman
ApplikationIP, ELISA, WB
Validierungen
  • collections(3)
Kat. Nr.ABIN948256
Menge100 μg
ReaktivitätHuman
ApplikationELISA, WB
Validierungen
  • collections(2)
Kat. Nr.ABIN562217
Menge100 μg
ReaktivitätHuman
ApplikationIA, IHC (p), WB
Validierungen
  • (4)
Kat. Nr.ABIN7041639
Menge1 mL

Empfohlene PI3 ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
ReaktivitätHuman
Analytical MethodQuantitative Sandwich ELISA
Validierungen
  • (1)
  • collections(1)
Kat. Nr.ABIN6958441
Menge96 tests
ReaktivitätHuman
Analytical MethodQuantitative Sandwich ELISA
Validierungen
  • collections(1)
Kat. Nr.ABIN1672903
Menge96 tests
ReaktivitätHuman
Analytical MethodQuantitative Sandwich ELISA
Validierungen
  • collections(1)
Kat. Nr.ABIN6720164
Menge1 kit

Empfohlene PI3 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
ReaktivitätHuman
SourceInsect Cells
Validierungen
  • collections(1)
Kat. Nr.ABIN3079541
Menge1 mg
ReaktivitätHuman
SourceHuman Cells
Validierungen
  • collections(1)
Kat. Nr.ABIN2005095
Menge10 μg
ReaktivitätHuman
SourceEscherichia coli (E. coli)
Validierungen
  • collections(1)
Kat. Nr.ABIN1080483
Menge50 μg

Neueste Publikationen zu unseren PI3 Produkten

Olewicz-Gawlik, Trzybulska, Graniczna, Kuznar-Kaminska, Katulska, Batura-Gabryel, Frydrychowicz, Danczak-Pazdrowska, Mozer-Lisewska: "Serum alarm antiproteases in systemic sclerosis patients." in: Human immunology, Vol. 78, Issue 9, pp. 559-564, 2018 (PubMed).

Scott, Quach, Yang, Ardekani, Cabrera, Wilson, Messaoudi-Powers, Ghosh: "Matrix stiffness exerts biphasic control over monocyte-endothelial adhesion via Rho-mediated ICAM-1 clustering." in: Integrative biology : quantitative biosciences from nano to macro, Vol. 8, Issue 8, pp. 869-78, 2016 (PubMed). (Probematerial (Species): Human). Weitere Details: Western Blotting,Immunohistochemistry

McGovern, Meinert, de Veer, Hollier, Parker, Upton: "Attenuated kallikrein-related peptidase activity disrupts desquamation and leads to stratum corneum thickening in human skin equivalent models." in: The British journal of dermatology, 2016 (PubMed). Von den Autoren verwendete Methode: Western Blotting (WB)

Liu, Chen, Wu, Chen, Zhang: "Neutrophil serine proteases and their endogenous inhibitors in coronary artery ectasia patients." in: Anatolian journal of cardiology, Vol. 16, Issue 1, pp. 23-8, 2016 (PubMed).

Bermúdez-Humarán, Motta, Aubry, Kharrat, Rous-Martin, Sallenave, Deraison, Vergnolle, Langella: "Serine protease inhibitors protect better than IL-10 and TGF-? anti-inflammatory cytokines against mouse colitis when delivered by recombinant lactococci." in: Microbial cell factories, Vol. 14, pp. 26, 2015 (PubMed).

Hellwig, Yoo, Reß, Andres, Braun, Schlegel, Wölfl: "Fulminant skin GvHD with a cytokine pattern resemblant of cytokine release syndrome successfully treated with multimodal immunosuppression including tocilizumab." in: Pediatric blood & cancer, Vol. 62, Issue 11, pp. 2033-5, 2015 (PubMed).

Qundos, Hong, Tybring, Divers, Odeberg, Uhlen, Nilsson, Schwenk: "Profiling post-centrifugation delay of serum and plasma with antibody bead arrays." in: Journal of proteomics, Vol. 95, pp. 46-54, 2013 (PubMed).

Gambichler, Demetriou, Terras, Bechara, Skrygan: "The impact of salt water soaks on biophysical and molecular parameters in psoriatic epidermis equivalents." in: Dermatology (Basel, Switzerland), Vol. 223, Issue 3, pp. 230-8, 2012 (PubMed). (Probematerial (Species): Human). Weitere Details: Sample: Tissue Lysate (EpiDerm-200 tissue models)

Wei, Hellström, Hellström: "Elafin selectively regulates the sensitivity of ovarian cancer cells to genotoxic drug-induced apoptosis." in: Gynecologic oncology, Vol. 125, Issue 3, pp. 727-33, 2012 (PubMed). Weitere Details: Sample: Cell Lysate (EOC cell lines from Humans and 1 mouse)

Huh, Oono, Shirafuji, Akiyama, Arata, Sakaguchi, Huh, Iwatsuki: "Dynamic alteration of human beta-defensin 2 localization from cytoplasm to intercellular space in psoriatic skin." in: Journal of molecular medicine (Berlin, Germany), Vol. 80, Issue 10, pp. 678-84, 2002 (PubMed).

Synonyme und alternative Namen zu PI3

peptidase inhibitor 3 (PI3), peptidase inhibitor 3, skin-derived (SKALP) (PI3), cementoin, elafin, ESI, SKALP, trappin-2, TRAPPIN-2, WAP3, WFDC14

Gen-IDs für verschiedene Spezies

GENE ID SPEZIES
5266 Homo sapiens
458276 Pan troglodytes
477241 Canis lupus familiaris
574237 Macaca mulatta
641305 Ovis aries
100137037 Pongo abelii
100137495 Papio anubis
783871 Bos taurus
396757 Sus scrofa
102172734 Capra hircus
101752219 Gallus gallus

Bezeichner auf Proteinebene für PI3

  • PI-3
  • WAP four-disulfide core domain 14
  • WAP four-disulfide core domain protein 14
  • elafin
  • elastase-specific inhibitor
  • pre-elafin
  • protease inhibitor 3, skin-derived (SKALP)
  • protease inhibitor WAP3
  • skin-derived antileukoproteinase
  • trappin-2
  • elafin preproprotein
  • peptidase inhibitor 3, skin-derived (SKALP)
  • TRAPPIN-2 protein
  • trappin ovine homolog
  • peptidase inhibitor 3, skin-derived
  • trappin 8
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