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PIAS3 Produkte

(Protein Inhibitor of Activated STAT, 3 (PIAS3))
This gene encodes a member of the PIAS [protein inhibitor of activated STAT (signal transducer and activator of transcription)] family of transcriptional modulators. The protein functions as a SUMO (small ubiquitin-like modifier)-E3 ligase which catalyzes the covalent attachment of a SUMO protein to specific target substrates. It directly binds to several transcription factors and either blocks or enhances their activity. Alternatively spliced transcript variants of this gene have been identified, but the full-length nature of some of these variants has not been determined. [provided by RefSeq, Jul 2008].

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Ausgewählte PIAS3 Kategorien

PIAS3 Antikörper

High quality antibodies with extensive validation data.

PIAS3 ELISA Kits

Reliable ELISA kits for a wide range of species.

PIAS3 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene PIAS3 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human, Mouse, Rat
Applikation WB, IHC, ELISA, IF, ICC
Validierungen
  • (4)
Kat. Nr. ABIN6264198
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, IHC (p)
Validierungen
  • (7)
  • (2)
Kat. Nr. ABIN1882115
Menge 400 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, IHC (p)
Validierungen
  • (8)
  • (2)
Kat. Nr. ABIN1882116
Menge 400 μL
Datenblatt Datenblatt

Empfohlene PIAS3 ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6958916
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human, Mouse, Rat
Analytical Method Qualitative Cell ELISA
Validierungen
Kat. Nr. ABIN1381422
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
Kat. Nr. ABIN6206678
Menge 96 tests
Datenblatt Datenblatt

Empfohlene PIAS3 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1314994
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1314993
Menge 25 μg
Datenblatt Datenblatt
Reaktivität Human
Source Insect Cells
Validierungen
  • (1)
Kat. Nr. ABIN3094547
Menge 1 mg
Datenblatt Datenblatt

Neueste Publikationen zu unseren PIAS3 Produkten

Sun, Li, Dong, Dong: "Characterization of nuclear localization and SUMOylation of the ATBF1 transcription factor in epithelial cells." in: PLoS ONE, Vol. 9, Issue 3, pp. e92746, (2014) (PubMed).

Castillo-Lluva, Tatham, Jones, Jaffray, Edmondson, Hay, Malliri: "SUMOylation of the GTPase Rac1 is required for optimal cell migration." in: Nature cell biology, Vol. 12, Issue 11, pp. 1078-85, (2010) (PubMed).

Spoden, Morandell, Ehehalt, Fiedler, Jansen-Dürr, Hermann, Zwerschke: "The SUMO-E3 ligase PIAS3 targets pyruvate kinase M2." in: Journal of cellular biochemistry, Vol. 107, Issue 2, pp. 293-302, (2009) (PubMed).

Brantley, Nabors, Gillespie, Choi, Palmer, Harrison, Roarty, Benveniste: "Loss of protein inhibitors of activated STAT-3 expression in glioblastoma multiforme tumors: implications for STAT-3 activation and gene expression." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 14, Issue 15, pp. 4694-704, (2008) (PubMed).

Iwasaki, Hailemariam, Tsuji: "PIAS3 interacts with ATF1 and regulates the human ferritin H gene through an antioxidant-responsive element." in: The Journal of biological chemistry, Vol. 282, Issue 31, pp. 22335-43, (2007) (PubMed).

Wetzler, Brady, Tracy, Li, Donohue, OLoughlin, Cheng, Mortazavi, McDonald, Kunapuli, Wallace, Baer, Cowell, Baumann: "Arsenic trioxide affects signal transducer and activator of transcription proteins through alteration of protein tyrosine kinase phosphorylation." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 12, Issue 22, pp. 6817-25, (2006) (PubMed).

Nojiri, Joh, Miura, Sakata, Nomura, Nakao, Sobue, Ohara, Asai, Ito: "ATBF1 enhances the suppression of STAT3 signaling by interaction with PIAS3." in: Biochemical and biophysical research communications, Vol. 314, Issue 1, pp. 97-103, (2004) (PubMed).

Long, Wang, Matsuura, He, Liu: "Activation of Smad transcriptional activity by protein inhibitor of activated STAT3 (PIAS3)." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 101, Issue 1, pp. 99-104, (2004) (PubMed).

Cheng, Zhang, Zhou, Marasco: "Down-regulation of SHP1 and up-regulation of negative regulators of JAK/STAT signaling in HTLV-1 transformed cell lines and freshly transformed human peripheral blood CD4+ T-cells." in: Leukemia research, Vol. 28, Issue 1, pp. 71-82, (2003) (PubMed).

Yamamoto, Sato, Sekine, Yumioka, Imoto, Junicho, Fuse, Matsuda: "Molecular interactions between STAT3 and protein inhibitor of activated STAT3, and androgen receptor." in: Biochemical and biophysical research communications, Vol. 306, Issue 2, pp. 610-5, (2003) (PubMed).

Synonyme und alternative Namen zu PIAS3

protein inhibitor of activated STAT 3 (PIAS3), protein inhibitor of activated STAT 3 (pias3), protein inhibitor of activated STAT 3 (Pias3), protein inhibitor of activated STAT, 3 (Pias3), protein inhibitor of activated STAT 3 L homeolog (pias3.L), PIAS3, Pias3l, ZMIZ5

Bezeichner auf Proteinebene für PIAS3

  • protein inhibitor of activated STAT, 3
  • E3 SUMO-protein ligase PIAS3-like
  • e3 SUMO-protein ligase PIAS3-like
  • E3 SUMO-protein ligase PIAS3
  • protein inhibitor of activated STAT protein 3
  • zinc finger, MIZ-type containing 5
  • KChAP
  • potassium channel regulatory protein KChAP
  • potassium channel-associated protein
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