PHOX2A Produkte
(Paired-Like Homeobox 2a (PHOX2A))
Kategorien
The protein encoded by this gene contains a paired-like homeodomain most similar to that of the Drosophila aristaless gene product. The encoded protein plays a central role in development of the autonomic nervous system. It regulates the expression of tyrosine hydroxylase and dopamine beta-hydroxylase, two catecholaminergic biosynthetic enzymes essential for the differentiation and maintenance of the noradrenergic neurotransmitter phenotype. The encoded protein has also been shown to regulate transcription of the alpha3 nicotinic acetylcholine receptor gene. Mutations in this gene have been associated with autosomal recessive congenital fibrosis of the extraocular muscles. [provided by RefSeq, Jul 2008].
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Ausgewählte PHOX2A Kategorien
PHOX2A Antikörper
High quality antibodies with extensive validation data.
PHOX2A Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene PHOX2A Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IF, RNAi
Validierungen
- (5)
Kat. Nr.
ABIN559952
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IF
Validierungen
- (2)
Kat. Nr.
ABIN2565772
Menge
50 μg
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
ELISA, IHC
Validierungen
- (1)
Kat. Nr.
ABIN7162523
Menge
100 μg
Datenblatt
Datenblatt
Empfohlene PHOX2A Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1314942
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1314944
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Tobacco (Nicotiana tabacum)
Validierungen
Kat. Nr.
ABIN3086044
Menge
1 mg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren PHOX2A Produkten
: "Effects of transcription factors Phox2 on expression of norepinephrine transporter and dopamine beta-hydroxylase in SK-N-BE(2)C cells." in: Journal of neurochemistry, Vol. 110, Issue 5, pp. 1502-13, (2009) (PubMed).: "The paired-like homeodomain protein, Arix, mediates protein kinase A-stimulated dopamine beta-hydroxylase gene transcription through its phosphorylation status." in: The Journal of biological chemistry, Vol. 277, Issue 25, pp. 22915-24, (2002) (PubMed).
: "Granzyme B-mediated apoptosis proceeds predominantly through a Bcl-2-inhibitable mitochondrial pathway." in: The Journal of biological chemistry, Vol. 276, Issue 15, pp. 12060-7, (2001) (PubMed).
: "The three-dimensional structure of human granzyme B compared to caspase-3, key mediators of cell death with cleavage specificity for aspartic acid in P1." in: Chemistry & biology, Vol. 8, Issue 4, pp. 357-68, (2001) (PubMed).
: "Direct cleavage of the human DNA fragmentation factor-45 by granzyme B induces caspase-activated DNase release and DNA fragmentation." in: The EMBO journal, Vol. 20, Issue 12, pp. 3101-13, (2001) (PubMed).
: "Granzyme B short-circuits the need for caspase 8 activity during granule-mediated cytotoxic T-lymphocyte killing by directly cleaving Bid." in: Molecular and cellular biology, Vol. 20, Issue 11, pp. 3781-94, (2000) (PubMed).
: "Granzyme A loading induces rapid cytolysis and a novel form of DNA damage independently of caspase activation." in: Immunity, Vol. 10, Issue 5, pp. 585-94, (1999) (PubMed).
: "Granzyme A initiates an alternative pathway for granule-mediated apoptosis." in: Immunity, Vol. 10, Issue 5, pp. 595-605, (1999) (PubMed).
Synonyme und alternative Namen zu PHOX2A
paired like homeobox 2a (PHOX2A), paired-like homeobox 2a (Phox2a), paired-like homeobox 2a (phox2a), paired like homeobox 2a S homeolog (phox2a.S), paired-like homeobox 2a (PHOX2A), ARIX, Arix, arix, CFEOM2, FEOM2, NCAM2, Phox2, phox2, Pmx2, PMX2A, Pmx2a, sou, xphox2a, zgc:77364Bezeichner auf Proteinebene für PHOX2A
- ARIX1 homeodomain protein
- aristaless homeobox homolog
- aristaless homeobox protein homolog
- arix homeodomain protein
- paired mesoderm homeobox protein 2A
- PHOX2A homeodomain protein
- aristaless homeobox gene homolog
- paired mesoderm homeobox 2a
- aristaless homeobox
- soulless
- paired-like (aristaless) homeobox 2a
Haben Sie etwas anderes gesucht?
- Photoreceptor Cell Specific Nuclear Receptor
- Phosphotyrosine
- Phosphotransacetylase
- Phosphothreonine
- Phosphoserine
- Phosphorylase, Glycogen, Muscle
- Phosphorylase B
- Phosphorylase A
- phosphoribosyl Pyrophosphate Synthetase 1
- Phospholipid-binding Lipoprotein mlaA
- Phospholipase D4
- Phospholipase D2
- Phospholipase D
- Phospholipase C gamma 2
- Phospholipase C gamma 1
- Phospholipase C delta 3
- Phospholipase C beta 4
- Phospholipase C beta 2
- Phospholipase C beta 1
- Phospholipase B
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