PITX2 Antikörper (Paired-Like Homeodomain 2)

Details for Product anti-PITX2 Antibody No. ABIN6568954
Target
Reaktivität
Human, Maus, Ratte
67
7
5
3
3
3
3
2
2
1
1
1
1
1
1
Wirt
Kaninchen
61
6
1
Klonalität
Polyklonal
Konjugat
Dieser PITX2 Antikörper ist unkonjugiert
6
5
5
4
4
4
1
1
1
1
1
1
Applikation
Western Blotting (WB)
56
44
8
6
2
1
1
1
1
Optionen
Immunogen A synthetic peptide of human PITX2
Isotyp IgG
Reinigung Affinity purification
Target
Andere Bezeichnung PITX2 (PITX2 Antibody Abstract)
Hintergrund

Synonyms: Paired Like Homeodomain 2,Paired-Like Homeodomain Transcription Factor 2,ALL1-Responsive Protein ARP1,Homeobox Protein PITX2,Solurshin,RIEG1,ARP1,RIEG,RGS,Rieg Bicoid-Related Homeobox Transcription Factor 1,RIEG Bicoid-Related Homeobox Transcription Factor,Paired-Like Homeodomain 2,All1-Responsive Gene 1.

Background: This gene encodes a member of the RIEG/PITX homeobox family, which is in the bicoid class of homeodomain proteins. The encoded protein acts as a transcription factor and regulates procollagen lysyl hydroxylase gene expression. This protein plays a role in the terminal differentiation of somatotroph and lactotroph cell phenotypes, is involved in the development of the eye, tooth and abdominal organs, and acts as a transcriptional regulator involved in basal and hormone-regulated activity of prolactin. Mutations in this gene are associated with Axenfeld-Rieger syndrome, iridogoniodysgenesis syndrome, and sporadic cases of Peters anomaly. A similar protein in other vertebrates is involved in the determination of left-right asymmetry during development. Alternatively spliced transcript variants encoding distinct isoforms have been described.

Molekulargewicht

Observed_MW: 34kDa

Calculated_MW: 30kDa/35kDa

Gen-ID 5308
UniProt Q99697
Pathways Retinoic Acid Receptor Signaling Pathway, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
Applikations-hinweise WB 1:500 - 1:2000
Beschränkungen Nur für Forschungszwecke einsetzbar
Konzentration 1 mg/mL
Buffer Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20°C. Avoid freeze / thaw cycles.
Bilder
Image no. 1 for anti-Paired-Like Homeodomain 2 (PITX2) antibody (ABIN6568954) Western blot analysis of extracts of various cell lines, using PITX2 antibody.