PITX2 Produkte
(Paired-Like Homeodomain 2 (PITX2))
Kategorien
This gene encodes a member of the RIEG/PITX homeobox family, which is in the bicoid class of homeodomain proteins. The encoded protein acts as a transcription factor and regulates procollagen lysyl hydroxylase gene expression. This protein plays a role in the terminal differentiation of somatotroph and lactotroph cell phenotypes, is involved in the development of the eye, tooth and abdominal organs, and acts as a transcriptional regulator involved in basal and hormone-regulated activity of prolactin. Mutations in this gene are associated with Axenfeld-Rieger syndrome, iridogoniodysgenesis syndrome, and sporadic cases of Peters anomaly. A similar protein in other vertebrates is involved in the determination of left-right asymmetry during development. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008].
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Ausgewählte PITX2 Kategorien
PITX2 Antikörper
High quality antibodies with extensive validation data.
PITX2 ELISA Kits
Reliable ELISA kits for a wide range of species.
PITX2 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene PITX2 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IHC, IF
Validierungen
- (4)
Kat. Nr.
ABIN7163465
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IF
Validierungen
- (2)
- (3)
Kat. Nr.
ABIN562251
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Cow, Dog, Human, Mouse, Pig, Rabbit, Rat
Applikation
WB, IHC
Validierungen
- (1)
- (4)
Kat. Nr.
ABIN2776373
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene PITX2 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Chicken
Analytical Method
Quantitative Sandwich ELISA
Validierungen
Kat. Nr.
ABIN6231839
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene PITX2 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN2752892
Menge
2 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1315183
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1315185
Menge
10 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren PITX2 Produkten
: "Functional corneal endothelium derived from corneal stroma stem cells of neural crest origin by retinoic acid and Wnt/?-catenin signaling." in: Stem cells and development, Vol. 22, Issue 5, pp. 828-39, (2013) (PubMed).: "PITX2 is involved in stress response in cultured human trabecular meshwork cells through regulation of SLC13A3." in: Investigative ophthalmology & visual science, Vol. 52, Issue 10, pp. 7625-33, (2011) (PubMed).
: "Human PRKC apoptosis WT1 regulator is a novel PITX2-interacting protein that regulates PITX2 transcriptional activity in ocular cells." in: The Journal of biological chemistry, Vol. 284, Issue 50, pp. 34829-38, (2009) (PubMed).
: "PITX2 gain-of-function induced defects in mouse forelimb development." in: BMC developmental biology, Vol. 8, pp. 25, (2008) (PubMed).
: "Absence of PITX2, BARX1, and FOXC1 mutations in De Hauwere syndrome (Axenfeld-Rieger anomaly, hydrocephaly, hearing loss): a 25-year follow up." in: American journal of medical genetics. Part A, Vol. 143A, Issue 11, pp. 1227-30, (2007) (PubMed).
: "Cytogenetically invisible microdeletions involving PITX2 in Rieger syndrome." in: Clinical genetics, Vol. 72, Issue 5, pp. 464-70, (2007) (PubMed).
: "Variants conferring risk of atrial fibrillation on chromosome 4q25. ..." in: Nature, Vol. 448, Issue 7151, pp. 353-7, (2007) (PubMed).
Synonyme und alternative Namen zu PITX2
paired like homeodomain 2 (PITX2), paired-like homeodomain transcription factor 2 (Pitx2), paired-like homeodomain 2 (pitx2), paired-like homeodomain 2 (Pitx2), paired like homeodomain 2 S homeolog (pitx2.S), paired like homeodomain 2 (pitx2), paired like homeodomain 2 L homeolog (pitx2.L), paired like homeodomain 2 (Pitx2), 9430085M16Rik, ARP1, arp1, Brx1, brx1, Brx1a, Brx1b, IDG2, idg2, IGDS, igds, IGDS2, igds2, IHG2, ihg2, IRID2, irid2, Munc30, Otlx2, otlx2, pitx-2, pitx2, pitx2-A, Pitx2a, pitx2a, Pitx2b, Pitx2c, pitx2c, Pitx2cbeta, PTX2, Ptx2, ptx2, RGS, rgs, RIEG, Rieg, rieg, RIEG1, rieg1, RS, xpitx2, xPtx2, XPtx2b, zgc:110508Bezeichner auf Proteinebene für PITX2
- ALL1-responsive protein ARP1
- all1-responsive gene 1
- homeobox protein PITX2
- paired-like homeodomain transcription factor 2
- pituitary homeobox 2
- rieg bicoid-related homeobox transcription factor 1
- solurshin
- BRX1 homeoprotein
- orthodenticle-like homeobox 2
- paired-like homeodomain transcription factor Munc 30
- paired-like homeodomain transcription factor 2a
- pitx2b
- homeodomain transcription factor 2
- rPtx2
- cPITX2
- transcription factor Pitx2
- homeodomain transcription factor Pitx2
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