PITX2 Antikörper (AA 122-151)

Produktnummer ABIN3032141

Produktdetails anti-PITX2 Antikörper

Target: PITX2 (Paired-Like Homeodomain 2 (PITX2))

Bindungsspezifität: AA 122-151

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PITX2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Kreuzreaktivität (Details): Expected species reactivity: Mouse, Rat, Chicken, Zebrafish, Xenopus

Aufreinigung: Antigen affinity purified

Immunogen: A portion of amino acids 122-151 from the human protein was used as the immunogen for this PITX2 antibody.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Titration of the PITX2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Immunofluorescence: 1:10-1:50,Western blot: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the PITX2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Details zu PITX2

Target: PITX2 (Paired-Like Homeodomain 2 (PITX2))

Andere Bezeichnung: PITX2 (PITX2 Produkte)

Synonyme: ARP1 antikoerper, Brx1 antikoerper, IDG2 antikoerper, IGDS antikoerper, IGDS2 antikoerper, IHG2 antikoerper, IRID2 antikoerper, Otlx2 antikoerper, PTX2 antikoerper, RGS antikoerper, RIEG antikoerper, RIEG1 antikoerper, RS antikoerper, 9430085M16Rik antikoerper, Brx1a antikoerper, Brx1b antikoerper, Munc30 antikoerper, Pitx2a antikoerper, Pitx2b antikoerper, Pitx2c antikoerper, Pitx2cbeta antikoerper, Ptx2 antikoerper, Rieg antikoerper, pitx2a antikoerper, pitx2c antikoerper, zgc:110508 antikoerper, XPtx2b antikoerper, xPtx2 antikoerper, xpitx2 antikoerper, arp1 antikoerper, brx1 antikoerper, idg2 antikoerper, igds antikoerper, igds2 antikoerper, ihg2 antikoerper, irid2 antikoerper, otlx2 antikoerper, pitx2-A antikoerper, ptx2 antikoerper, rgs antikoerper, rieg antikoerper, rieg1 antikoerper, pitx-2 antikoerper, pitx2 antikoerper, paired like homeodomain 2 antikoerper, paired-like homeodomain transcription factor 2 antikoerper, paired-like homeodomain 2 antikoerper, paired like homeodomain 2 S homeolog antikoerper, paired like homeodomain 2 L homeolog antikoerper, PITX2 antikoerper, Pitx2 antikoerper, pitx2 antikoerper, pitx2.S antikoerper, pitx2.L antikoerper

Hintergrund: Pilx2 is a member of the RIEG/PITX homeobox family, which is in the bicoid class of homeodomain proteins. This protein acts as a transcription factor and regulates procollagen lysyl hydroxylase gene expression. It plays a role in the terminal differentiation of somatotroph and lactotroph cell phenotypes, is involved in the development of the eye, tooth and abdominal organs, and acts as a transcriptional regulator involved in basal and hormone-regulated activity of prolactin. Mutations in this protein are associated with Axenfeld-Rieger syndrome, iridogoniodysgenesis syndrome, and sporadic cases of Peters anomaly. A similar protein in other vertebrates is involved in the determination of left-right asymmetry during development.

UniProt: Q99697

Pathways: Retinoic Acid Receptor Signaling Pathway, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development