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FGFR2 Antikörper

FGFR2 Reaktivität: Human, Maus, Ratte WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6567470
  • Target Alle FGFR2 Antikörper anzeigen
    FGFR2 (Fibroblast Growth Factor Receptor 2 (FGFR2))
    Reaktivität
    • 136
    • 71
    • 50
    • 11
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 123
    • 12
    • 1
    Kaninchen
    Klonalität
    • 115
    • 21
    Polyklonal
    Konjugat
    • 57
    • 13
    • 8
    • 7
    • 6
    • 6
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser FGFR2 Antikörper ist unkonjugiert
    Applikation
    • 79
    • 55
    • 47
    • 40
    • 29
    • 17
    • 13
    • 13
    • 11
    • 10
    • 3
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Aufreinigung
    Affinity purification
    Immunogen
    Recombinant protein of human FGFR2
    Isotyp
    IgG
    Top Product
    Discover our top product FGFR2 Primärantikörper
  • Applikationshinweise
    WB 1:500 - 1:2000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    1 mg/mL
    Buffer
    Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    FGFR2 (Fibroblast Growth Factor Receptor 2 (FGFR2))
    Andere Bezeichnung
    FGFR2 (FGFR2 Produkte)
    Synonyme
    FGFR2 antikoerper, FGFR2IIIb antikoerper, bek antikoerper, bfr-1 antikoerper, cd332 antikoerper, cek3 antikoerper, cfd1 antikoerper, ect1 antikoerper, fgfr-2 antikoerper, jws antikoerper, k-sam antikoerper, kgfr antikoerper, tk14 antikoerper, tk25 antikoerper, xfgfr2 antikoerper, DKFZp469H1521 antikoerper, BBDS antikoerper, BEK antikoerper, BFR-1 antikoerper, CD332 antikoerper, CEK3 antikoerper, CFD1 antikoerper, ECT1 antikoerper, JWS antikoerper, K-SAM antikoerper, KGFR antikoerper, TK14 antikoerper, TK25 antikoerper, AU043015 antikoerper, AW556123 antikoerper, Bek antikoerper, Fgfr-2 antikoerper, Fgfr-7 antikoerper, Fgfr7 antikoerper, KGFRTr antikoerper, svs antikoerper, FGF-R antikoerper, fgfr72IIIb antikoerper, FGFR antikoerper, fc56c05 antikoerper, wu:fc56c05 antikoerper, fibroblast growth factor receptor 2 antikoerper, fibroblast growth factor receptor 2 L homeolog antikoerper, FGFR2 antikoerper, LOC100084641 antikoerper, fgfr2 antikoerper, Fgfr2 antikoerper, fgfr2.L antikoerper
    Hintergrund

    Synonyms: bacteria-expressed kinase,BBDS,BEK,BEK fibroblast growth factor receptor,BFR1,CD332,CD332 antigen,CEK3,CFD1,Craniofacial dysostosis 1,ECT1,FGF receptor,FGFR 2,FGFR-2,Fgfr2,FGFR2,Fibroblast growth factor receptor 2,Hydroxyaryl protein kinase,Jackson Weiss syndrome,JWS,K SAM,K-sam,Keratinocyte growth factor receptor 2,Keratinocyte growth factor receptor,KGFR,KSAM,protein tyrosine kinase,receptor like 14,soluble FGFR4 variant 4,TK14,TK25

    Background: The protein encoded by this gene is a member of the fibroblast growth factor receptor family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein consists of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This particular family member is a high-affinity receptor for acidic, basic and/or keratinocyte growth factor, depending on the isoform. Mutations in this gene are associated with Crouzon syndrome, Pfeiffer syndrome, Craniosynostosis, Apert syndrome, Jackson-Weiss syndrome, Beare-Stevenson cutis gyrata syndrome, Saethre-Chotzen syndrome, and syndromic craniosynostosis. Multiple alternatively spliced transcript variants encoding different isoforms have been noted for this gene.

    Molekulargewicht

    Observed_MW: 110kDa

    Calculated_MW: 28kDa/40kDa/76-92kDa

    Gen-ID
    2263
    UniProt
    P21802
    Pathways
    RTK Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Growth Factor Binding
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