GCLC Antikörper

Produktnummer ABIN6566902

Produktdetails anti-GCLC Antikörper

Target: GCLC (Glutamate-Cysteine Ligase, Catalytic Subunit (GCLC))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GCLC Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: Affinity purification

Immunogen: Recombinant protein of human GCLC

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu GCLC

Target: GCLC (Glutamate-Cysteine Ligase, Catalytic Subunit (GCLC))

Andere Bezeichnung: GCLC (GCLC Produkte)

Synonyme: GCLC antikoerper, gclc antikoerper, MGC146287 antikoerper, 2259 antikoerper, CG2259 antikoerper, DmGCLC antikoerper, DmGCS antikoerper, DmGCSh antikoerper, Dmel\\CG2259 antikoerper, GCL antikoerper, GCLc antikoerper, GCSh antikoerper, Gcs antikoerper, Gcsh antikoerper, DDBDRAFT_0186120 antikoerper, DDBDRAFT_0231403 antikoerper, DDB_0186120 antikoerper, DDB_0231403 antikoerper, GCS antikoerper, GLCL antikoerper, GLCLC antikoerper, D9Wsu168e antikoerper, GLCL-H antikoerper, Ggcs-hs antikoerper, Glclc antikoerper, cb1049 antikoerper, fe36e11 antikoerper, wu:fe36e11 antikoerper, glutamate-cysteine ligase catalytic subunit antikoerper, glutamate-cysteine ligase, catalytic subunit antikoerper, Glutamate-cysteine ligase catalytic subunit antikoerper, gamma glutamylcysteine synthetase antikoerper, glutamate-cysteine ligase, catalytic subunit L homeolog antikoerper, glutamate-cysteine ligase, catalytic subunit S homeolog antikoerper, gamma-glutamylcysteine synthetase antikoerper, GCLC antikoerper, gclc antikoerper, Gclc antikoerper, LbGCS antikoerper, gcsA antikoerper, gclc.L antikoerper, gclc.S antikoerper, GSH1 antikoerper

Hintergrund:

Synonyms: EC 6.3.2.2,Gamma ECS,Gamma glutamylcysteine synthetase,Gamma-ECS,Gamma-glutamylcysteine synthetase,GCL,Gclc,GCS,GCS heavy chain,GLCL,GLCLC,Glutamate cysteine ligase catalytic subunit,Glutamate--cysteine ligase catalytic subunit,GSH1

Background: Glutamate-cysteine ligase, also known as gamma-glutamylcysteine synthetase is the first rate-limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subunit and a light regulatory subunit. This locus encodes the catalytic subunit, while the regulatory subunit is derived from a different gene located on chromosome 1p22-p21. Mutations at this locus have been associated with hemolytic anemia due to deficiency of gamma-glutamylcysteine synthetase and susceptibility to myocardial infarction.

Molekulargewicht:

Observed_MW: 72kDa

Calculated_MW: 72kDa

Gen-ID: 2729

UniProt: P48506

Pathways: Cell RedoxHomeostasis