Glutamate-Cysteine Ligase, Catalytic Subunit (GCLC) (AA 528-637) Antikörper

Details zu Produkt Nr. ABIN561050
Antigen
  • GCLC
  • gclc
  • MGC146287
  • 2259
  • CG2259
  • DmGCLC
  • DmGCS
  • DmGCSh
  • Dmel\\CG2259
  • GCL
  • GCLc
  • GCSh
  • Gcs
  • Gcsh
  • DDBDRAFT_0186120
  • DDBDRAFT_0231403
  • DDB_0186120
  • DDB_0231403
  • GCS
  • GLCL
  • GLCLC
  • D9Wsu168e
  • GLCL-H
  • Ggcs-hs
  • Glclc
  • cb1049
  • fe36e11
  • wu:fe36e11
  • glutamate-cysteine ligase catalytic subunit
  • glutamate-cysteine ligase, catalytic subunit
  • Glutamate-cysteine ligase catalytic subunit
  • gamma glutamylcysteine synthetase
  • glutamate-cysteine ligase, catalytic subunit L homeolog
  • glutamate-cysteine ligase, catalytic subunit S homeolog
  • gamma-glutamylcysteine synthetase
  • GCLC
  • gclc
  • Gclc
  • LbGCS
  • gcsA
  • gclc.L
  • gclc.S
  • GSH1
Epitop
AA 528-637
14
12
10
10
9
9
8
7
6
3
3
3
2
2
2
1
1
1
Reaktivität
Human
113
59
54
11
10
6
4
3
3
2
1
1
1
1
1
1
1
1
Wirt
Maus
119
6
Klonalität (Klon)
Monoklonal ()
Konjugat
Unkonjugiert
7
5
5
4
4
4
3
3
3
3
3
3
1
1
1
1
1
Applikation
Immunofluorescence (IF), ELISA, Western Blotting (WB)
95
45
39
21
18
16
15
13
9
4
2
1
Optionen
Immunogen GCLC (NP_001489, 528 a.a. ~ 637 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Immunogen sequence: EGVFPGLIPI LNSYLENMEV DVDTRCSILN YLKLIKKRAS GELMTVARWM REFIANHPDY KQDSVITDEM NYSLILKCNQ IANELCECPE LLGSAFRKVK YSGSKTDSSN
Klon 3H1
Isotyp IgG1 kappa
Kreuzreaktivität Human, Maus, Ratte (Rattus)
Antigen
Andere Bezeichnung GCLC (GCLC Antibody Abstract)
Hintergrund Full Gene Name: glutamate-cysteine ligase, catalytic subunit
Synonyms: GCS,GLCL,GLCLC
Gen-ID 2729
NCBI Accession NP_001489, NM_001498
Pathways Cell RedoxHomeostasis
Applikations-hinweise Optimal working dilution should be determined by the investigator.
Kommentare

Product Quality tested by: Antibody Reactive Against Recombinant Protein.

Beschränkungen Nur für Forschungszwecke einsetzbar
Buffer In 1x PBS, pH 7.4
Handhabung Aliquot to avoid repeated freezing and thawing.
Lagerung -20 °C
Informationen zur Lagerung Store at -20 °C or lower. Aliquot to avoid repeated freezing and thawing.
Bilder des Herstellers
Immunofluorescence (IF) image for anti-Glutamate-Cysteine Ligase, Catalytic Subunit (GCLC) (AA 528-637) antibody (ABIN561050) Immunofluorescence of monoclonal antibody to GCLC on HeLa cell. [antibody concentrati...
Western Blotting (WB) image for anti-Glutamate-Cysteine Ligase, Catalytic Subunit (GCLC) (AA 528-637) antibody (ABIN561050) GCLC monoclonal antibody (M01), clone 3H1 Western Blot analysis of GCLC expression in...
ELISA image for anti-Glutamate-Cysteine Ligase, Catalytic Subunit (GCLC) (AA 528-637) antibody (ABIN561050) Detection limit for recombinant GST tagged GCLC is approximately 0.03ng/ml as a captu...
Western Blotting (WB) image for anti-Glutamate-Cysteine Ligase, Catalytic Subunit (GCLC) (AA 528-637) antibody (ABIN561050) Western Blot analysis of GCLC expression in transfected 293T cell line by GCLC monocl...
 image for anti-Glutamate-Cysteine Ligase, Catalytic Subunit (GCLC) (AA 528-637) antibody (ABIN561050) Western Blot detection against Immunogen (37.84 KDa) .
Western Blotting (WB) image for anti-Glutamate-Cysteine Ligase, Catalytic Subunit (GCLC) (AA 528-637) antibody (ABIN561050) GCLC monoclonal antibody (M01), clone 3H1. Western Blot analysis of GCLC expression i...
Western Blotting (WB) image for anti-Glutamate-Cysteine Ligase, Catalytic Subunit (GCLC) (AA 528-637) antibody (ABIN561050) GCLC monoclonal antibody (M01), clone 3H1. Western Blot analysis of GCLC expression i...
Produkt verwendet in: Sugiyama, Ebinuma, Nakamoto, Sakasegawa, Murakami, Chu, Usui, Ishibashi, Wakayama, Taniki, Murata, Saito, Fukasawa, Saito, Yamagishi, Wakita, Takaku, Hibi, Saito, Kanai: "Prominent steatosis with hypermetabolism of the cell line permissive for years of infection with hepatitis C virus." in: PLoS ONE, Vol. 9, Issue 4, pp. e94460, 2014 (PubMed).

Venè, Cardinali, Arena, Ferrari, Benelli, Minghelli, Poggi, Noonan, Albini, Tosetti: "Glycogen synthase kinase 3 regulates cell death and survival signaling in tumor cells under redox stress." in: Neoplasia (New York, N.Y.), Vol. 16, Issue 9, pp. 710-22, 2014 (PubMed).

Li, Gunter, Fukagawa: "Differential activation of the inflammasome in THP-1 cells exposed to chrysotile asbestos and Libby "six-mix" amphiboles and subsequent activation of BEAS-2B cells." in: Cytokine, Vol. 60, Issue 3, pp. 718-30, 2012 (PubMed).

Fan, Liu, Hao, Wang, Robinson, Monnier: "The LEGSKO mouse: a mouse model of age-related nuclear cataract based on genetic suppression of lens glutathione synthesis." in: PLoS ONE, Vol. 7, Issue 11, pp. e50832, 2012 (PubMed).

Abel, Bubel, Simper, Powell, McClellan, Andreeff, MacLeod, DiGiovanni: "Protection against 2-chloroethyl ethyl sulfide (CEES)-induced cytotoxicity in human keratinocytes by an inducer of the glutathione detoxification pathway." in: Toxicology and applied pharmacology, Vol. 255, Issue 2, pp. 176-83, 2011 (PubMed).

Hardwick, Fisher, Canet, Lake, Cherrington: "Diversity in antioxidant response enzymes in progressive stages of human nonalcoholic fatty liver disease." in: Drug metabolism and disposition: the biological fate of chemicals, Vol. 38, Issue 12, pp. 2293-301, 2010 (PubMed).

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