DYRK1A Antikörper
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- Target Alle DYRK1A Antikörper anzeigen
- DYRK1A (Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 1A (DYRK1A))
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser DYRK1A Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Aufreinigung
- Affinity purification
- Immunogen
- Recombinant protein of human DYRK1A
- Isotyp
- IgG
- Top Product
- Discover our top product DYRK1A Primärantikörper
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- Applikationshinweise
- WB 1:500 - 1:1000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 1 mg/mL
- Buffer
- Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- DYRK1A (Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 1A (DYRK1A))
- Andere Bezeichnung
- DYRK1A (DYRK1A Produkte)
- Synonyme
- DYRK1A antikoerper, dyrk antikoerper, dyrk1 antikoerper, hp86 antikoerper, mnb antikoerper, mnbh antikoerper, DYRK antikoerper, DYRK1 antikoerper, HP86 antikoerper, MNB antikoerper, MNBH antikoerper, MRD7 antikoerper, 2310043O08Rik antikoerper, D16Ertd272e antikoerper, D16Ertd493e antikoerper, Dyrk antikoerper, ENSMUSG00000074897 antikoerper, Gm10783 antikoerper, Mnbh antikoerper, Mp86 antikoerper, mmb antikoerper, PSK47 antikoerper, dual specificity tyrosine phosphorylation regulated kinase 1A antikoerper, dual specificity tyrosine-(Y)-phosphorylation regulated kinase 1A antikoerper, dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1a antikoerper, dual specificity tyrosine-(Y)-phosphorylation regulated kinase 1A S homeolog antikoerper, DYRK1A antikoerper, dyrk1a antikoerper, Dyrk1a antikoerper, dyrk1a.S antikoerper
- Hintergrund
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Synonyms: Dual specificity tyrosine phosphorylation regulated kinase,Dual specificity tyrosine (Y) phosphorylation regulated kinase 1A,Dual specificity tyrosine phosphorylation regulated kinase 1,Dual specificity tyrosine phosphorylation regulated kinase 1A,Dual specificity tyrosine-phosphorylation-regulated kinase 1A,Dual specificity YAK 1 related kinase,Dual specificity YAK1 related kinase,Dual specificity YAK1-related kinase,DYR1A,DYRK 1,DYRK 1A,DYRK,DYRK1,Dyrk1a,DYRKA,hMNB,HP 86,HP86,Minibrain (Drosophila) homolog,Minibrain homolog,Minibrain,Drosophila,homolog of,MNB,MNB protein kinase,Mnb protein kinase homolog hp86,MNB protein kinase,Serine/threonine-specific,MNB/DYRK protein kinase,MNBH,MRD7,OTTHUMP00000109090,OTTHUMP00000109091,OTTHUMP00000109094,OTTHUMP00000174799,Protein kinase minibrain homolog,Serine/threonine kinase MNB
Background: This gene encodes a member of the Dual-specificity tyrosine phosphorylation-regulated kinase (DYRK) family. This member contains a nuclear targeting signal sequence, a protein kinase domain, a leucine zipper motif, and a highly conservative 13-consecutive-histidine repeat. It catalyzes its autophosphorylation on serine/threonine and tyrosine residues. It may play a significant role in a signaling pathway regulating cell proliferation and may be involved in brain development. This gene is a homolog of Drosophila mnb (minibrain) gene and rat Dyrk gene. It is localized in the Down syndrome critical region of chromosome 21, and is considered to be a strong candidate gene for learning defects associated with Down syndrome. Alternative splicing of this gene generates several transcript variants differing from each other either in the 5' UTR or in the 3' coding region. These variants encode at least five different isoforms.
- Molekulargewicht
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Observed_MW: 72kDa
Calculated_MW: 60kDa/61kDa/66kDa/84kDa/85kDa
- Gen-ID
- 1859
- UniProt
- Q13627
- Pathways
- Mitotic G1-G1/S Phases
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