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DYRK1A Antikörper (N-Term)

DYRK1A Reaktivität: Human, Maus WB, IHC (p) Wirt: Kaninchen Polyclonal RB13055 unconjugated
Produktnummer ABIN391798
  • Target Alle DYRK1A Antikörper anzeigen
    DYRK1A (Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 1A (DYRK1A))
    Bindungsspezifität
    • 15
    • 9
    • 9
    • 8
    • 7
    • 7
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 107-136, N-Term
    Reaktivität
    • 73
    • 29
    • 22
    • 6
    • 5
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    Human, Maus
    Wirt
    • 67
    • 4
    • 2
    • 1
    Kaninchen
    Klonalität
    • 70
    • 4
    Polyklonal
    Konjugat
    • 38
    • 6
    • 6
    • 5
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser DYRK1A Antikörper ist unkonjugiert
    Applikation
    • 74
    • 43
    • 14
    • 13
    • 13
    • 11
    • 8
    • 6
    • 5
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Homologie
    Rat, X
    Aufreinigung
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    Immunogen
    This DYRK1A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 107-136 amino acids from the N-terminal region of human DYRK1A.
    Klon
    RB13055
    Isotyp
    Ig Fraction
    Top Product
    Discover our top product DYRK1A Primärantikörper
  • Applikationshinweise
    WB: 1:500-1:2000. IHC-P: 1:50~100
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Haltbarkeit
    6 months
  • Target
    DYRK1A (Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 1A (DYRK1A))
    Andere Bezeichnung
    DYRK1A (DYRK1A Produkte)
    Synonyme
    DYRK1A antikoerper, dyrk antikoerper, dyrk1 antikoerper, hp86 antikoerper, mnb antikoerper, mnbh antikoerper, DYRK antikoerper, DYRK1 antikoerper, HP86 antikoerper, MNB antikoerper, MNBH antikoerper, MRD7 antikoerper, 2310043O08Rik antikoerper, D16Ertd272e antikoerper, D16Ertd493e antikoerper, Dyrk antikoerper, ENSMUSG00000074897 antikoerper, Gm10783 antikoerper, Mnbh antikoerper, Mp86 antikoerper, mmb antikoerper, PSK47 antikoerper, dual specificity tyrosine phosphorylation regulated kinase 1A antikoerper, dual specificity tyrosine-(Y)-phosphorylation regulated kinase 1A antikoerper, dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1a antikoerper, dual specificity tyrosine-(Y)-phosphorylation regulated kinase 1A S homeolog antikoerper, DYRK1A antikoerper, dyrk1a antikoerper, Dyrk1a antikoerper, dyrk1a.S antikoerper
    Hintergrund
    DYRK1A is a member of the Dual-specificity tyrosine phosphorylation-regulated kinase (DYRK) family. This member contains a nuclear targeting signal sequence, a protein kinase domain, a leucine zipper motif, and a highly conservative 13-consecutive-histidine repeat. It catalyzes its autophosphorylation on serine/threonine and tyrosine residues. It may play a significant role in a signaling pathway regulating cell proliferation and may be involved in brain development. The DYRK1A gene is a homolog of Drosophila mnb (minibrain) gene and rat Dyrk gene. It is localized in the Down syndrome critical region of chromosome 21, and is considered to be a strong candidate gene for learning defects associated with Down syndrome.
    Molekulargewicht
    85584
    Gen-ID
    1859
    NCBI Accession
    NP_001387, NP_567824, NP_569120, NP_569122
    UniProt
    Q13627
    Pathways
    Mitotic G1-G1/S Phases
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