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IGF1R Antikörper (N-Term)
IGF1R
Reaktivität: Human
WB, IF, FACS, IHC (p)
Wirt: Kaninchen
Polyclonal
RB15292
unconjugated
Produktnummer ABIN2841778
Produktdetails anti-IGF1R Antikörper
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Target
Alle IGF1R Antikörper anzeigen
IGF1R
(Insulin-Like Growth Factor 1 Receptor (IGF1R))
Bindungsspezifität
Alle Epitope für IGF1R Antikörper
AA 51-77, N-Term
Reaktivität
Alle Reaktivitäten für IGF1R Antikörper
Human
Wirt
Alle Wirte für IGF1R Antikörper
Kaninchen
Klonalität
Alle Klonalitäten für IGF1R Antikörper
Polyklonal
Konjugat
Alle Konjugate für IGF1R Antikörper
Dieser IGF1R Antikörper ist unkonjugiert
Applikation
Alle Applikationen für IGF1R Antikörper
Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Homologie
M, Rat
Aufreinigung
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Immunogen
This IGF1R antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 51-77 amino acids from the N-terminal region of human IGF1R.
Klon
RB15292
Isotyp
Ig Fraction
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Discover our top product IGF1R Primärantikörper
Alternativen
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Anwendungsinformationen
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Applikationshinweise
IF: 1:10~50. WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Format
Liquid
Buffer
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C,-20 °C
Informationen zur Lagerung
Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Haltbarkeit
6 months
Details zu IGF1R
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Target
IGF1R
(Insulin-Like Growth Factor 1 Receptor (IGF1R))
Andere Bezeichnung
IGF1R (IGF1R Produkte )
Synonyme
CMT2N antikoerper, CD221 antikoerper, IGFIR antikoerper, IGFR antikoerper, JTK13 antikoerper, IGFIRC antikoerper, IGFR1 antikoerper, IGF-1R antikoerper, IGF1R antikoerper, DKFZp469I0618 antikoerper, igf-1r antikoerper, xIGF-1R antikoerper, xIGFR antikoerper, xigf1r antikoerper, A330103N21Rik antikoerper, D930020L01 antikoerper, hyft antikoerper, igf-ir antikoerper, IGF-IR antikoerper, IGF-IRb antikoerper, wu:fb03h06 antikoerper, IGF-IRa antikoerper, sb:eu1090 antikoerper, wu:fi20b10 antikoerper, alanyl-tRNA synthetase antikoerper, insulin like growth factor 1 receptor antikoerper, insulin-like growth factor 1 receptor antikoerper, insulin-like growth factor 1 antikoerper, insulin-like growth factor I receptor antikoerper, insulin like growth factor 1 receptor S homeolog antikoerper, insulin-like growth factor 1b receptor antikoerper, insulin-like growth factor 1a receptor antikoerper, AARS antikoerper, IGF1R antikoerper, Igf1r antikoerper, igf1r antikoerper, Igf1 antikoerper, LOC780503 antikoerper, LOC100136427 antikoerper, igf1r.S antikoerper, igf1rb antikoerper, igf1ra antikoerper
Hintergrund
The IGF1R receptor binds insulin-like growth factor with a high affinity and plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. The protein possess tyrosine kinase activity.
Molekulargewicht
154793
Gen-ID
3480
NCBI Accession
NP_000866
UniProt
P08069
Pathways
RTK Signalweg , Regulation of Hormone Metabolic Process , Regulation of Hormone Biosynthetic Process , Autophagie
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