ATP6V1H Antikörper (C-Term)

Produktnummer ABIN651375

Produktdetails anti-ATP6V1H Antikörper

Target: ATP6V1H (ATPase, H+ Transporting, Lysosomal 50/57kDa, V1 Subunit H (ATP6V1H))

Bindungsspezifität: AA 400-426, C-Term

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ATP6V1H Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Homologie: B, Pig

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This ATP6V1H antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 400-426 amino acids from the C-terminal region of human ATP6V1H.

Klon: RB25984

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Details zu ATP6V1H

Target: ATP6V1H (ATPase, H+ Transporting, Lysosomal 50/57kDa, V1 Subunit H (ATP6V1H))

Andere Bezeichnung: ATP6V1H (ATP6V1H Produkte)

Synonyme: MSTP042 antikoerper, NBP1 antikoerper, SFD antikoerper, SFDalpha antikoerper, SFDbeta antikoerper, VMA13 antikoerper, V-ATPASE antikoerper, 0710001F19Rik antikoerper, AU022349 antikoerper, CGI-11 antikoerper, chunp6890 antikoerper, ATPase H+ transporting V1 subunit H antikoerper, ATPase, H+ transporting, lysosomal V1 subunit H antikoerper, ATP6V1H antikoerper, Atp6v1h antikoerper, atp6v1h antikoerper

Hintergrund: ATP6V1H encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c', and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This gene encodes the regulatory H subunit of the V1 domain which is required for catalysis of ATP but not the assembly of V-ATPase.

Molekulargewicht: 55883

Gen-ID: 51606

NCBI Accession: NP_057025, NP_998784, NP_998785

UniProt: Q9UI12

Pathways: Transition Metal Ion Homeostasis, Proton Transport