ATP6V1H Antikörper (Internal Region)

Produktnummer ABIN6287269

Produktdetails anti-ATP6V1H Antikörper

Target: ATP6V1H (ATPase, H+ Transporting, Lysosomal 50/57kDa, V1 Subunit H (ATP6V1H))

Bindungsspezifität: AA 310-390, Internal Region

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ATP6V1H Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Verwendungszweck: V-ATPase H is a protein encoded by the ATP6V1H gene which is approximately 55,9 kDa. V-ATPase H is localised to the cytosol. It is involved in insulin receptor recycling and innate immune system. It is a multi-subunit enzyme that mediates acidification of intracellular organelles. V-ATPase-dependent organelle acidification is necessary for multiple processes including protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. Subunit H activates the ATPase activity of the enzyme and couples ATPase activity to proton flow. V-ATPase H is widely expressed. Mutations in the ATP6V1H gene may result in an involvement in the HIV life cycle. STJ96226 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This polyclonal antibody detects endogenous levels of V-ATPase H protein.

Spezifität: V-ATPase H Polyclonal Antibody detects endogenous levels of V-ATPase H protein.

Produktmerkmale: Rabbit polyclonal to V-ATPase H.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human V-ATPase H

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000
IHC 1:100-1:300
ELISA 1:20000

Kommentare:

Widely expressed.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C, and avoid repeat freeze-thaw cycles.

Details zu ATP6V1H

Target: ATP6V1H (ATPase, H+ Transporting, Lysosomal 50/57kDa, V1 Subunit H (ATP6V1H))

Andere Bezeichnung: V-ATPase H (ATP6V1H Produkte)

Synonyme: MSTP042 antikoerper, NBP1 antikoerper, SFD antikoerper, SFDalpha antikoerper, SFDbeta antikoerper, VMA13 antikoerper, V-ATPASE antikoerper, 0710001F19Rik antikoerper, AU022349 antikoerper, CGI-11 antikoerper, chunp6890 antikoerper, ATPase H+ transporting V1 subunit H antikoerper, ATPase, H+ transporting, lysosomal V1 subunit H antikoerper, ATP6V1H antikoerper, Atp6v1h antikoerper, atp6v1h antikoerper

Molekulargewicht: 55 kDa

Gen-ID: 51606

UniProt: Q9UI12

Pathways: Transition Metal Ion Homeostasis, Proton Transport