DKK1 Antikörper

Produktnummer ABIN643515

Produktdetails anti-DKK1 Antikörper

Target: DKK1 (Dickkopf Homolog 1 (DKK1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DKK1 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Verwendungszweck: Rabbit Anti-Human DKK1

Spezifität: DS-PB-00648 recognizes human Dickkopf (Xenopus laevis) homolog 1 (DKK1), a 35kDa to 50kDa member of the dickkopf family. It is expressed in the placenta, prostate and to a lesser extent, in the colon and spleen. DKK1 is secreted when expressed in 293T cells. DKK1 inhibits Wnt signalling in embryonic development, most likely acting upstream of frizzled. It is also thought to contribute to neoplastic processes, inhibit osteoblast differentiation and is associated with the presence of osteolytic bone lesions in patients with multiple myeloma.

Aufreinigung: Purified

Immunogen: Synthetic human DKK1 - KLH conjugated.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Immunohistology - Paraffin

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: IgG concentration 1.0 mg/ml

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: -20°C

Referenzen für anti-DKK1 Antikörper (ABIN643515)

de Andrade, de Castro, Vicente, da Rosa, Nader, Pereira, Fröde: "Evaluation of circulating levels of inflammatory and bone formation markers in axial spondyloarthritis." in: International immunopharmacology, Vol. 21, Issue 2, pp. 481-6, (2014) (PubMed).

Details zu DKK1

Target: DKK1 (Dickkopf Homolog 1 (DKK1))

Andere Bezeichnung: DKK1 (DKK1 Produkte)

Synonyme: DKK-1 antikoerper, SK antikoerper, AI414495 antikoerper, SGY antikoerper, SGY-1 antikoerper, SGY1 antikoerper, Soggy antikoerper, mSgy antikoerper, dkk1 antikoerper, dkk antikoerper, dkk-1 antikoerper, xdkk1 antikoerper, Xdkk-1 antikoerper, Dickkopf1 antikoerper, dickkopf-1 antikoerper, mdkk-1 antikoerper, dkk1-A antikoerper, dickkopf WNT signaling pathway inhibitor 1 antikoerper, dickkopf like acrosomal protein 1 antikoerper, dickkopf-related protein 1 antikoerper, dickkopf-like 1 antikoerper, dickkopf WNT signaling pathway inhibitor 1b antikoerper, dickkopf protein antikoerper, dickkopf WNT signaling pathway inhibitor 1 S homeolog antikoerper, DKK1 antikoerper, Dkk1 antikoerper, DKKL1 antikoerper, LOC100228789 antikoerper, Dkkl1 antikoerper, dkk1b antikoerper, dkk1 antikoerper, dickkopf antikoerper, dkk1.S antikoerper

Pathways: WNT Signalweg, Regulation of Muscle Cell Differentiation, Positive Regulation of fat Cell Differentiation