129-10010 specifically recognizes human ABCB5 (ATP-binding cassette sub-family B member 5), a P-glycoprotein and member of the conserved ABC transporter family, which acts as an energy-dependent efflux transporter for rhodamine. ABCB5 is primarily expressed by skin progenitor cells and shown to act as a regulator of cell fusion and determinant of membrane potential. Studies have revealed the expression of ABCB5 in human malignant melanoma tumors, and in particular its association with CD133 + stem cell phenotype- expressing cells
Produktmerkmale
Goat Anti-Human ABCB5
Aufreinigung
Purified
Immunogen
Peptide sequence C-QTQHRNTSKKAQ from the internal region of ABCB5 (NP_848654.3)