ABCB5 Antikörper (N-Term)

Produktnummer ABIN390068

Produktdetails anti-ABCB5 Antikörper

Target: ABCB5 (ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 5 (ABCB5))

Bindungsspezifität: AA 1-30, N-Term

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ABCB5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS)

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This ABCB5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human ABCB5.

Klon: RB16781

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. WB: 1:2000. WB: 1:2000. WB: 1:1000. FC: 1:25. FC: 1:10~50. FC: 1:10~50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid freeze-thaw cycles.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots.

Haltbarkeit: 6 months

Referenzen für anti-ABCB5 Antikörper (ABIN390068)

Ksander, Kolovou, Wilson, Saab, Guo, Ma, McGuire, Gregory, Vincent, Perez, Cruz-Guilloty, Kao, Call, Tucker, Zhan, Murphy, Lathrop, Alt, Mortensen, Lin, Zieske, Frank, Frank: "ABCB5 is a limbal stem cell gene required for corneal development and repair." in: Nature, Vol. 511, Issue 7509, pp. 353-7, (2014) (PubMed).

Freeman, Gray, Millward, Pearce, Ziman: "Evaluation of a multi-marker immunomagnetic enrichment assay for the quantification of circulating melanoma cells." in: Journal of translational medicine, Vol. 10, pp. 192, (2013) (PubMed).

Luo, Ellis, Dallaglio, Takeda, Robinson, Robinson, Liu, Lewis, McCarter, Gonzalez, Norris, Roop, Spritz, Ahn, Fujita: "Side population cells from human melanoma tumors reveal diverse mechanisms for chemoresistance." in: The Journal of investigative dermatology, Vol. 132, Issue 10, pp. 2440-50, (2012) (PubMed).

Lai, Schwartz, Hsu: "CD133+ melanoma subpopulations contribute to perivascular niche morphogenesis and tumorigenicity through vasculogenic mimicry." in: Cancer research, Vol. 72, Issue 19, pp. 5111-8, (2012) (PubMed).

Wilson, Schatton, Zhan, Gasser, Ma, Saab, Schanche, Waaga-Gasser, Gold, Huang, Murphy, Frank, Frank: "ABCB5 identifies a therapy-refractory tumor cell population in colorectal cancer patients." in: Cancer research, Vol. 71, Issue 15, pp. 5307-16, (2011) (PubMed).

Ramgolam, Lauriol, Lalou, Lauden, Michel, de la Grange, Khatib, Aoudjit, Charron, Alcaide-Loridan, Al-Daccak: "Melanoma spheroids grown under neural crest cell conditions are highly plastic migratory/invasive tumor cells endowed with immunomodulator function." in: PLoS ONE, Vol. 6, Issue 4, pp. e18784, (2011) (PubMed).

Details zu ABCB5

Target: ABCB5 (ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 5 (ABCB5))

Andere Bezeichnung: ABCB5 (ABCB5 Produkte)

Synonyme: ABCB5alpha antikoerper, ABCB5beta antikoerper, EST422562 antikoerper, 9230106F14Rik antikoerper, RGD1566342 antikoerper, ABCB5 antikoerper, mdr1 antikoerper, im:7158730 antikoerper, wu:fc18f02 antikoerper, wu:fi81f06 antikoerper, ATP binding cassette subfamily B member 5 antikoerper, ATP-binding cassette, sub-family B (MDR/TAP), member 5 antikoerper, ATP-binding cassette sub-family B member 5 antikoerper, ABCB5 antikoerper, Abcb5 antikoerper, abcb5 antikoerper, TGME49_249820 antikoerper, PAAG_04387 antikoerper, VDBG_00160 antikoerper, VDBG_02292 antikoerper

Hintergrund: ABCB5 belongs to the ATP-binding cassette (ABC) transporter superfamily of integral membrane proteins. These proteins participate in ATP-dependent transmembrane transport of structurally diverse molecules ranging from small ions, sugars, and peptides to more complex organic molecules.

Molekulargewicht: 138641

Gen-ID: 340273

NCBI Accession: NP_001157413, NP_001157414, NP_001157465, NP_848654

UniProt: Q2M3G0