Insulin Receptor Antikörper (Middle Region)
Kurzübersicht für Insulin Receptor Antikörper (Middle Region) (ABIN636083)
Target
Alle Insulin Receptor (INSR) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- Middle Region
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Spezifität
- INSR antibody was raised against the middle region of INSR
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Aufreinigung
- Affinity purified
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Immunogen
- INSR antibody was raised using the middle region of INSR corresponding to a region with amino acids ENNVVHLMWQEPKEPNGLIVLYEVSYRRYGDEELHLCVSRKHFALERGCR
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Applikationshinweise
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WB: 1 µg/mL
Optimal conditions should be determined by the investigator. -
Kommentare
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INSR Blocking Peptide, (ABIN937998), is also available for use as a blocking control in assays to test for specificity of this INSR antibody
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Lyophilized powder. Add distilled water for a 1 mg/mL concentration of INSR antibody in PBS
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Konzentration
- Lot specific
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Buffer
- PBS
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Handhabung
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Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. -
Lagerung
- 4 °C/-20 °C
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Informationen zur Lagerung
- Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
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- Insulin Receptor (INSR)
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Andere Bezeichnung
- INSR
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Hintergrund
- This receptor binds insulin and has a tyrosine-protein kinase activity. Isoform Short has a higher affinity for insulin. INSR mediates the metabolic functions of insulin.
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Molekulargewicht
- 154 kDa (MW of target protein)
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Pathways
- NF-kappaB Signalweg, RTK Signalweg, AMPK Signaling, Carbohydrate Homeostasis, Regulation of Cell Size, Regulation of Carbohydrate Metabolic Process, Growth Factor Binding, Negative Regulation of Transporter Activity
Target
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