Cyclin D2 Antikörper
-
- Target Alle Cyclin D2 (CCND2) Antikörper anzeigen
- Cyclin D2 (CCND2)
- Reaktivität
- Human, Maus, Ratte
-
Wirt
- Kaninchen
-
Klonalität
- Polyklonal
-
Konjugat
- Dieser Cyclin D2 Antikörper ist unkonjugiert
- Applikation
- Bitte anfragen
- Verwendungszweck
- Rabbit Anti-Cyclin D2 (Ab-280) Antibody,
- Top Product
- Discover our top product CCND2 Primärantikörper
-
-
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- 2-8°C (short-term), -20°C (long-term)
-
- Target
- Cyclin D2 (CCND2)
- Andere Bezeichnung
- Cyclin D2 (CCND2 Produkte)
- Synonyme
- si:ch211-240j22.2 antikoerper, ccnd2 antikoerper, CCND2 antikoerper, kiak0002 antikoerper, zgc:162280 antikoerper, LOC100224096 antikoerper, KIAK0002 antikoerper, BF642806 antikoerper, C86853 antikoerper, Vin-1 antikoerper, Vin1 antikoerper, cD2 antikoerper, 2600016F06Rik antikoerper, AI256817 antikoerper, cyclin D2, b antikoerper, cyclin D2 S homeolog antikoerper, cyclin D2 antikoerper, G1/S-specific cyclin-D2 antikoerper, cyclin D2, a antikoerper, cyclin D2 L homeolog antikoerper, ccnd2b antikoerper, ccnd2.S antikoerper, CCND2 antikoerper, ccnd2 antikoerper, ccnd2a antikoerper, Ccnd2 antikoerper, ccnd2.L antikoerper
- Hintergrund
-
Target Description: Regulatory component of the cyclin D2-CDK4 (DC) complex that phosphorylates and inhibits members of the retinoblastoma (RB) protein family including RB1 and regulates the cell-cycle during G(1)/S transition. Phosphorylation of RB1 allows dissociation of the transcription factor E2F from the RB/E2F complex and the subsequent transcription of E2F target genes which are responsible for the progression through the G(1) phase. Hypophosphorylates RB1 in early G(1) phase. Cyclin D-CDK4 complexes are major integrators of various mitogenenic and antimitogenic signals. Also substrate for SMAD3, phosphorylating SMAD3 in a cell-cycle-dependent manner and repressing its transcriptional activity. Component of the ternary complex, cyclin D2/CDK4/CDKN1B, required for nuclear translocation and activity of the cyclin D-CDK4 complex (By similarity).
Gene Symbol: CCND2
- Gen-ID
- 894
- UniProt
- P30279
- Pathways
- Zellzyklus, Mitotic G1-G1/S Phases
-