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Cyclin D2 Antikörper

CCND2 Reaktivität: Human, Maus, Ratte Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6298006
  • Target Alle Cyclin D2 (CCND2) Antikörper anzeigen
    Cyclin D2 (CCND2)
    Reaktivität
    Human, Maus, Ratte
    Wirt
    • 77
    • 24
    Kaninchen
    Klonalität
    • 80
    • 21
    Polyklonal
    Konjugat
    • 51
    • 6
    • 6
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser Cyclin D2 Antikörper ist unkonjugiert
    Applikation
    Bitte anfragen
    Verwendungszweck
    Rabbit Anti-Cyclin D2 (Ab-280) Antibody,
    Top Product
    Discover our top product CCND2 Primärantikörper
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    2-8°C (short-term), -20°C (long-term)
  • Target
    Cyclin D2 (CCND2)
    Andere Bezeichnung
    Cyclin D2 (CCND2 Produkte)
    Synonyme
    si:ch211-240j22.2 antikoerper, ccnd2 antikoerper, CCND2 antikoerper, kiak0002 antikoerper, zgc:162280 antikoerper, LOC100224096 antikoerper, KIAK0002 antikoerper, BF642806 antikoerper, C86853 antikoerper, Vin-1 antikoerper, Vin1 antikoerper, cD2 antikoerper, 2600016F06Rik antikoerper, AI256817 antikoerper, cyclin D2, b antikoerper, cyclin D2 S homeolog antikoerper, cyclin D2 antikoerper, G1/S-specific cyclin-D2 antikoerper, cyclin D2, a antikoerper, cyclin D2 L homeolog antikoerper, ccnd2b antikoerper, ccnd2.S antikoerper, CCND2 antikoerper, ccnd2 antikoerper, ccnd2a antikoerper, Ccnd2 antikoerper, ccnd2.L antikoerper
    Hintergrund

    Target Description: Regulatory component of the cyclin D2-CDK4 (DC) complex that phosphorylates and inhibits members of the retinoblastoma (RB) protein family including RB1 and regulates the cell-cycle during G(1)/S transition. Phosphorylation of RB1 allows dissociation of the transcription factor E2F from the RB/E2F complex and the subsequent transcription of E2F target genes which are responsible for the progression through the G(1) phase. Hypophosphorylates RB1 in early G(1) phase. Cyclin D-CDK4 complexes are major integrators of various mitogenenic and antimitogenic signals. Also substrate for SMAD3, phosphorylating SMAD3 in a cell-cycle-dependent manner and repressing its transcriptional activity. Component of the ternary complex, cyclin D2/CDK4/CDKN1B, required for nuclear translocation and activity of the cyclin D-CDK4 complex (By similarity).

    Gene Symbol: CCND2

    Gen-ID
    894
    UniProt
    P30279
    Pathways
    Zellzyklus, Mitotic G1-G1/S Phases
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