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Ghrelin Antikörper

GHRL Reaktivität: Human, Ratte WB, IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6292644
  • Target Alle Ghrelin (GHRL) Antikörper anzeigen
    Ghrelin (GHRL)
    Reaktivität
    • 85
    • 55
    • 27
    • 8
    • 2
    Human, Ratte
    Wirt
    • 92
    • 20
    • 6
    • 1
    Kaninchen
    Klonalität
    • 100
    • 19
    Polyklonal
    Konjugat
    • 51
    • 11
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser Ghrelin Antikörper ist unkonjugiert
    Applikation
    • 66
    • 53
    • 27
    • 26
    • 26
    • 11
    • 11
    • 8
    • 8
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Aufreinigung
    Affinity purification
    Immunogen
    Recombinant protein of human GHRL
    Isotyp
    IgG
    Top Product
    Discover our top product GHRL Primärantikörper
  • Applikationshinweise
    WB 1:500 - 1:2000
    IHC 1:50 - 1:200
    Kommentare

    Highest level in stomach, All forms are found in serum as well, Other tissues compensate for the loss of ghrelin synthesis in the stomach following gastrectomy

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20C. Avoid freeze / thaw cycles.
  • Target
    Ghrelin (GHRL)
    Andere Bezeichnung
    GHRL (GHRL Produkte)
    Synonyme
    2210006E23Rik antikoerper, Ghr antikoerper, MTLRP antikoerper, MTLRPAP antikoerper, m46 antikoerper, Gh1-1 antikoerper, GRHL antikoerper, MTLRP-AP antikoerper, GHR antikoerper, ghrelin antikoerper, ghrelin and obestatin prepropeptide antikoerper, ghrelin/obestatin prepropeptide antikoerper, Ghrl antikoerper, GHRL antikoerper, ghrl antikoerper
    Hintergrund
    This gene encodes the ghrelin-obestatin preproprotein that is cleaved to yield two peptides, ghrelin and obestatin. Ghrelin is a powerful appetite stimulant and plays an important role in energy homeostasis. Its secretion is initiated when the stomach is empty, whereupon it binds to the growth hormone secretagogue receptor in the hypothalamus which results in the secretion of growth hormone (somatotropin). Ghrelin is thought to regulate multiple activities, including hunger, reward perception via the mesolimbic pathway, gastric acid secretion, gastrointestinal motility, and pancreatic glucose-stimulated insulin secretion. It was initially proposed that obestatin plays an opposing role to ghrelin by promoting satiety and thus decreasing food intake, but this action is still debated. Recent reports suggest multiple metabolic roles for obestatin, including regulating adipocyte function and glucose metabolism. Alternative splicing results in multiple transcript variants. In addition, antisense transcripts for this gene have been identified and may potentially regulate ghrelin-obestatin preproprotein expression.
    Molekulargewicht
    12.911 kDa
    Gen-ID
    51738
    UniProt
    Q9UBU3
    Pathways
    Positive Regulation of Peptide Hormone Secretion, Hormone Transport, Peptide Hormone Metabolism, Negative Regulation of Hormone Secretion, Synaptic Membrane, Feeding Behaviour
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