pi8 antikoerper, cap2 antikoerper, CAP-2 antikoerper, CAP2 antikoerper, NK10 antikoerper, Spi8 antikoerper, ovalbumin antikoerper, PI8 antikoerper, serpin family B member 8 antikoerper, serpin B8 antikoerper, serpin peptidase inhibitor, clade B (ovalbumin), member 8 antikoerper, serine (or cysteine) peptidase inhibitor, clade B, member 8 antikoerper, Serpinb8 antikoerper, SERPINB8 antikoerper, LOC607205 antikoerper, serpinb8 antikoerper, LOC100424017 antikoerper
Hintergrund
The protein encoded by this gene is a member of the ov-serpin family of serine protease inhibitors. The encoded protein is produced by platelets and can bind to and inhibit the function of furin, a serine protease involved in platelet functions. In addition, this protein has been found to enhance the mechanical stability of cell-cell adhesion in the skin, and defects in this gene have been associated with an autosomal-recessive form of exfoliative ichthyosis.