SERPINB8 Antikörper (C-Term)

Produktnummer ABIN2787992

Produktdetails anti-SERPINB8 Antikörper

Target: SERPINB8 (serpin Peptidase Inhibitor, Clade B (Ovalbumin), Member 8 (SERPINB8))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte, Kaninchen, Hund, Pferd, Rind (Kuh), Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SERPINB8 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: LVNAIYFKGK WNEQFDRKYT RGMLFKTNEE KKTVQMMFKE AKFKMGYADE

Homologie: Cow: 93%, Dog: 86%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 86%, Rabbit: 93%, Rat: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against SERPINB8. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human SERPINB8

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 242 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu SERPINB8

Target: SERPINB8 (serpin Peptidase Inhibitor, Clade B (Ovalbumin), Member 8 (SERPINB8))

Andere Bezeichnung: SERPINB8 (SERPINB8 Produkte)

Synonyme: pi8 antikoerper, cap2 antikoerper, CAP-2 antikoerper, CAP2 antikoerper, NK10 antikoerper, Spi8 antikoerper, ovalbumin antikoerper, PI8 antikoerper, serpin family B member 8 antikoerper, serpin B8 antikoerper, serpin peptidase inhibitor, clade B (ovalbumin), member 8 antikoerper, serine (or cysteine) peptidase inhibitor, clade B, member 8 antikoerper, Serpinb8 antikoerper, SERPINB8 antikoerper, LOC607205 antikoerper, serpinb8 antikoerper, LOC100424017 antikoerper

Hintergrund: The superfamily of high molecular weight serine proteinase inhibitors (serpins) regulate a diverse set of intracellular and extracellular processes such as complement activation, fibrinolysis, coagulation, cellular differentiation, tumor suppression, apoptosis, and cell migration. Serpins are characterized by well-conserved a tertiary structure that consists of 3 beta sheets and 8 or 9 alpha helices (Huber and Carrell, 1989 [PubMed 2690952]). A critical portion of the molecule, the reactive center loop connects beta sheets A and C. Protease inhibitor-8 (PI8, SERPINB8) is a member of the ov-serpin subfamily, which, relative to the archetypal serpin PI1 (MIM 107400), is characterized by a high degree of homology to chicken ovalbumin, lack of N- and C-terminal extensions, absence of a signal peptide, and a serine rather than an asparagine residue at the penultimate position (summary by Bartuski et al., 1997 [PubMed 9268635]).
Alias Symbols: CAP2, PI8
Protein Interaction Partner: SUMO2, LARS, UBC, CAP1, PRSS1, F10, F2, FURIN, BCL2,
Protein Size: 242

Molekulargewicht: 27 kDa

Gen-ID: 5271

NCBI Accession: NM_001031848, NP_001027018

UniProt: Q8N178