SERPINB8 Antikörper (C-Term)
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- Target Alle SERPINB8 Antikörper anzeigen
- SERPINB8 (serpin Peptidase Inhibitor, Clade B (Ovalbumin), Member 8 (SERPINB8))
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Bindungsspezifität
- C-Term
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Reaktivität
- Human, Maus, Ratte, Kaninchen, Hund, Pferd, Rind (Kuh), Meerschweinchen
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser SERPINB8 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- LVNAIYFKGK WNEQFDRKYT RGMLFKTNEE KKTVQMMFKE AKFKMGYADE
- Homologie
- Cow: 93%, Dog: 86%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 86%, Rabbit: 93%, Rat: 93%
- Produktmerkmale
- This is a rabbit polyclonal antibody against SERPINB8. It was validated on Western Blot.
- Aufreinigung
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the C terminal region of human SERPINB8
- Top Product
- Discover our top product SERPINB8 Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 242 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- SERPINB8 (serpin Peptidase Inhibitor, Clade B (Ovalbumin), Member 8 (SERPINB8))
- Andere Bezeichnung
- SERPINB8 (SERPINB8 Produkte)
- Synonyme
- pi8 antikoerper, cap2 antikoerper, CAP-2 antikoerper, CAP2 antikoerper, NK10 antikoerper, Spi8 antikoerper, ovalbumin antikoerper, PI8 antikoerper, serpin family B member 8 antikoerper, serpin B8 antikoerper, serpin peptidase inhibitor, clade B (ovalbumin), member 8 antikoerper, serine (or cysteine) peptidase inhibitor, clade B, member 8 antikoerper, Serpinb8 antikoerper, SERPINB8 antikoerper, LOC607205 antikoerper, serpinb8 antikoerper, LOC100424017 antikoerper
- Hintergrund
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The superfamily of high molecular weight serine proteinase inhibitors (serpins) regulate a diverse set of intracellular and extracellular processes such as complement activation, fibrinolysis, coagulation, cellular differentiation, tumor suppression, apoptosis, and cell migration. Serpins are characterized by well-conserved a tertiary structure that consists of 3 beta sheets and 8 or 9 alpha helices (Huber and Carrell, 1989 [PubMed 2690952]). A critical portion of the molecule, the reactive center loop connects beta sheets A and C. Protease inhibitor-8 (PI8, SERPINB8) is a member of the ov-serpin subfamily, which, relative to the archetypal serpin PI1 (MIM 107400), is characterized by a high degree of homology to chicken ovalbumin, lack of N- and C-terminal extensions, absence of a signal peptide, and a serine rather than an asparagine residue at the penultimate position (summary by Bartuski et al., 1997 [PubMed 9268635]).
Alias Symbols: CAP2, PI8
Protein Interaction Partner: SUMO2, LARS, UBC, CAP1, PRSS1, F10, F2, FURIN, BCL2,
Protein Size: 242 - Molekulargewicht
- 27 kDa
- Gen-ID
- 5271
- NCBI Accession
- NM_001031848, NP_001027018
- UniProt
- Q8N178
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