SERPINB8 Antikörper (C-Term)

Produktnummer ABIN1881791

Produktdetails anti-SERPINB8 Antikörper

Target: SERPINB8 (serpin Peptidase Inhibitor, Clade B (Ovalbumin), Member 8 (SERPINB8))

Bindungsspezifität: AA 274-301, C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SERPINB8 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This SERPINB8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 274-301 amino acids from the C-terminal region of human SERPINB8.

Klon: RB42352

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Haltbarkeit: 6 months

Details zu SERPINB8

Target: SERPINB8 (serpin Peptidase Inhibitor, Clade B (Ovalbumin), Member 8 (SERPINB8))

Andere Bezeichnung: SERPINB8 (SERPINB8 Produkte)

Synonyme: pi8 antikoerper, cap2 antikoerper, CAP-2 antikoerper, CAP2 antikoerper, NK10 antikoerper, Spi8 antikoerper, ovalbumin antikoerper, PI8 antikoerper, serpin family B member 8 antikoerper, serpin B8 antikoerper, serpin peptidase inhibitor, clade B (ovalbumin), member 8 antikoerper, serine (or cysteine) peptidase inhibitor, clade B, member 8 antikoerper, Serpinb8 antikoerper, SERPINB8 antikoerper, LOC607205 antikoerper, serpinb8 antikoerper, LOC100424017 antikoerper

Hintergrund: The superfamily of high molecular weight serine proteinase inhibitors (serpins) regulate a diverse set of intracellular and extracellular processes such as complement activation, fibrinolysis, coagulation, cellular differentiation, tumor suppression, apoptosis, and cell migration. Serpins are characterized by well-conserved a tertiary structure that consists of 3 beta sheets and 8 or 9 alpha helices (Huber and Carrell, 1989 [PubMed 2690952]). A critical portion of the molecule, the reactive center loop connects beta sheets A and C. Protease inhibitor-8 (PI8, SERPINB8) is a member of the ov-serpin subfamily, which, relative to the archetypal serpin PI1 (MIM 107400), is characterized by a high degree of homology to chicken ovalbumin, lack of N- and C-terminal extensions, absence of a signal peptide, and a serine rather than an asparagine residue at the penultimate position (summary by Bartuski et al., 1997 [PubMed 9268635]).

Molekulargewicht: 42767

NCBI Accession: NP_001027018, NP_001263419, NP_002631, NP_942130

UniProt: P50452