AKAP5 Antikörper

Produktnummer ABIN6291243

Produktdetails anti-AKAP5 Antikörper

Target: AKAP5 (A Kinase (PRKA) Anchor Protein 5 (AKAP5))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser AKAP5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF)

Aufreinigung: Affinity purification

Immunogen: Recombinant protein of human AKAP5

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500 - 1:2000
IF 1:50 - 1:200

Kommentare:

Predominantly in the cerebral cortex and the postsynaptic densities of the forebrain, and to a lesser extent in adrenal medulla, lung and anterior pituitary

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20C. Avoid freeze / thaw cycles.

Details zu AKAP5

Target: AKAP5 (A Kinase (PRKA) Anchor Protein 5 (AKAP5))

Andere Bezeichnung: AKAP5 (AKAP5 Produkte)

Synonyme: AKAP5 antikoerper, AKAP75 antikoerper, AKAP79 antikoerper, H21 antikoerper, AKAP antikoerper, P75 antikoerper, 3526401B18Rik antikoerper, AKAP 150 antikoerper, AKAP-5 antikoerper, AKAP150 antikoerper, BB098886 antikoerper, Gm258 antikoerper, P150 antikoerper, Akap79 antikoerper, A kinase (PRKA) anchor protein 5 antikoerper, A-kinase anchoring protein 5 antikoerper, AKAP5 antikoerper, Akap5 antikoerper

Substanzklasse: Viral Protein

Hintergrund: The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein binds to the RII-beta regulatory subunit of PKA, and also to protein kinase C and the phosphatase calcineurin. It is predominantly expressed in cerebral cortex and may anchor the PKA protein at postsynaptic densities (PSD) and be involved in the regulation of postsynaptic events. It is also expressed in T lymphocytes and may function to inhibit interleukin-2 transcription by disrupting calcineurin-dependent dephosphorylation of NFAT.

Molekulargewicht: 47.088 kDa

Gen-ID: 9495

UniProt: P24588

Pathways: cAMP Metabolic Process